X-linked lymphoproliferative disease: twenty-five years after the discovery

TA Seemayer, TG Gross, RM Egeler, SJ Pirruccello… - Pediatric …, 1995 - nature.com
The X-linked lymphoproliferative disease (XLP), one of six described X-linked immunodeficiencies,
stems from a mutation at Xq25 which renders males impotent to mount an effective …

Systemic administration of a phosphorothioate oligonucleotide with a sequence complementary to p53 for acute myelogenous leukemia and myelodysplastic …

…, HK Tewary, MA Arneson, SJ Pirruccello… - Antisense research …, 1993 - liebertpub.com
A synthetic phosphorothioate oligonucleotide was administered systemically to five patients
with either relapsed or refractory acute myelogenous leukemia (AML), or myelodysplastic …

The human B cell-associated antigen CD24 is a single chain sialoglycoprotein.

SJ Pirruccello, TW LeBien - Journal of immunology (Baltimore, Md …, 1986 - journals.aai.org
PIRRUCCELLO AND TUCKER W. LEBIEN~ … Pirruccello, S. J., and TW LeBien. 1985. …

Human Immunodeficiency Virus Type 1 Pathobiology Studied in Humanized BALB/c-Rag2−/−γc−/− Mice

…, H Sneller, L Walters, JG Sharp, SJ Pirruccello… - Journal of …, 2007 - Am Soc Microbiol
The specificity of human immunodeficiency virus type 1 (HIV-1) for human cells precludes
virus infection in most mammalian species and limits the utility of small animal models for …

Human immunodeficiency virus encephalitis in SCID mice.

…, E Flanagan, J Reinhard, SJ Pirruccello… - The American journal …, 1996 - ncbi.nlm.nih.gov
The human immunodeficiency virus (HIV) is neuroinvasive and commonly causes cognitive
and motor deficits during the later stages of viral infection.(referred to as HIV dementia). The …

Lymphocyte reconstitution after allogeneic blood stem cell transplantation for hematologic malignancies

ZS Pavletic, SS Joshi, SJ Pirruccello… - Bone marrow …, 1998 - nature.com
Forty-one patients were studied at set times after allogeneic blood stem cell transplantation (alloBSCT)
for recovery of lymphocyte numbers and function. Cells were mobilized with G-…

A hexameric phosphorothioate oligonucleotide telomerase inhibitor arrests growth of burkitt's lymphoma cellsin vitroandin vivo

JE Mata, SS Joshi, B Palen, SJ Pirruccello… - Toxicology and applied …, 1997 - Elsevier
A phosphorothioate oligonucleotide (PS-ODN) with sequence identical to the repeat
sequence of the mammalian telomere, 5′-d(TTAGGG)-3′, was incubated with a Burkitt's …

[PDF][PDF] Immunologic attributes of cytokine mobilized peripheral blood stem cells and recovery following transplantation

…, KC Mills, ML Thomas, SJ Pirruccello… - Bone marrow …, 1996 - academia.edu
The immunologic attributes of cytokine mobilized peripherai blood stem cell (PSC) products
(n= 52) and the resulting reconstitution of the hematopoietic and immunologic system …

Tumor suppressor functions of Dnmt3a and Dnmt3b in the prevention of malignant mouse lymphopoiesis

…, RA Hlady, J Opavska, D Klinkebiel, SJ Pirruccello… - Leukemia, 2014 - nature.com
1 Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C et al. A recurrent
germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. Nat …

[PDF][PDF] Promoter hypomethylation and expression is conserved in mouse chronic lymphocytic leukemia induced by decreased or inactivated Dnmt3a

…, D Klinkebiel, RA Hlady, A Suresh, SJ Pirruccello… - Cell Reports, 2016 - cell.com
DNA methyltransferase 3a (DNMT3A) catalyzes the formation of 5-methyl-cytosine in
mammalian genomic DNA, and it is frequently mutated in human hematologic malignancies. Bi-…