User profiles for SE Wenzel
Sally WenzelUniversity of Pittsburgh Verified email at pitt.edu Cited by 101134 |
Asthma phenotypes: the evolution from clinical to molecular approaches
SE Wenzel - Nature medicine, 2012 - nature.com
… These results suggest that, despite the relationship between asthma and atopy and allergy,
allergy per se may not be the pathobiological process that initiates asthma, and that other—…
allergy per se may not be the pathobiological process that initiates asthma, and that other—…
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome
…, RF Lemanske Jr, AJ Wardlaw, SE Wenzel… - Journal of Allergy and …, 2011 - Elsevier
It is increasingly clear that asthma is a complex disease made up of number of disease
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms of …
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms of …
Asthma: defining of the persistent adult phenotypes
SE Wenzel - The Lancet, 2006 - thelancet.com
The common disease asthma is probably not a single disease, but rather a complex of
multiple, separate syndromes that overlap. Although clinicians have recognised these different …
multiple, separate syndromes that overlap. Although clinicians have recognised these different …
Global strategy for asthma management and prevention: GINA executive summary
…, E Pizzichini, SD Sullivan, SE Wenzel… - European …, 2008 - Eur Respiratory Soc
Asthma is a serious health problem throughout the world. During the past two decades, many
scientific advances have improved our understanding of asthma and ability to manage and …
scientific advances have improved our understanding of asthma and ability to manage and …
International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A
Task Force, supported by the European Respiratory Society and American Thoracic Society, …
Task Force, supported by the European Respiratory Society and American Thoracic Society, …
Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program
WC Moore, DA Meyers, SE Wenzel… - American journal of …, 2010 - atsjournals.org
Rationale: The Severe Asthma Research Program cohort includes subjects with persistent
asthma who have undergone detailed phenotypic characterization. Previous univariate …
asthma who have undergone detailed phenotypic characterization. Previous univariate …
An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials …
…, SJ Szefler, MD Thomas, SE Wenzel - American journal of …, 2009 - atsjournals.org
Background: The assessment of asthma control is pivotal to the evaluation of treatment
response in individuals and in clinical trials. Previously, asthma control, severity, and …
response in individuals and in clinical trials. Previously, asthma control, severity, and …
[HTML][HTML] Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma
EH Bel, SE Wenzel, PJ Thompson… - New England journal …, 2014 - Mass Medical Soc
Background Many patients with severe asthma require regular treatment with oral glucocorticoids
despite the use of high-dose inhaled therapy. However, the regular use of systemic …
despite the use of high-dose inhaled therapy. However, the regular use of systemic …
Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics
SE Wenzel, LB Schwartz, EL Langmack… - American journal of …, 1999 - atsjournals.org
The mechanisms associated with the development of severe, corticosteroid (CS)-dependent
asthma are poorly understood, but likely heterogenous. It was hypothesized that severe …
asthma are poorly understood, but likely heterogenous. It was hypothesized that severe …
Bronchoscopic evaluation of severe asthma: persistent inflammation associated with high dose glucocorticoids
SE Wenzel, SJ Szefler, DYM Leung… - American journal of …, 1997 - atsjournals.org
The role of inflammation in the pathogenesis of severe asthma chronically treated with high
doses of glucocorticoids is poorly understood. Despite this, treatment has been aimed at …
doses of glucocorticoids is poorly understood. Despite this, treatment has been aimed at …