Linezolid is used off-label to treat multidrug-resistant tuberculosis (MDR-TB) in absence of
systematic evidence. We performed a systematic review and meta-analysis on efficacy, safety …

Poly(ADP-ribose) polymerase 1 (PARP1) is an important component of the base excision
repair (BER) pathway as well as a regulator of homologous recombination (HR) and non-…

Surgical resection is the only option of cure for patients with metastatic colorectal cancer (CRC).
However, the risk of recurrence within 18 mo after metastasectomy is around 75% and …

Epidermal growth factor (EGF)-related proteins such as transforming growth factor α (TGF-α)
control cancer cell growth through autocrine and paracrine pathways. Overexpression of …

Purpose: Poly(ADP-ribose) polymerase (PARP) inhibitors are undergoing extensive clinical
testing for their single-agent activity in homologous recombination (HR)-deficient tumors and …

A new amino-cupric silver protocol is described for detection of neuronal degeneration. We
describe its selectivity in visualizing both early and semiacute degeneration after …

Clinical experience on meropenem–clavulanate to treat tuberculosis (TB) is anecdotal (according
to case reports on 10 patients). The aim of our case–control study was to evaluate the …

No large study has ever evaluated the efficacy, safety and tolerability of meropenem/clavulanate
to treat multidrug- and extensively drug-resistant tuberculosis (MDR- and XDR-TB). The …

We investigated whether changes in iron metabolism and the transferrin receptor (TRF‐R)
expression were involved in the antileukaemic effects of arabinoside cytosine (ara‐C). …

High expression of the epidermal growth factor receptor (EGFR) has been implicated in the
development of squamous‐cell carcinomas of head and neck (SCCHN). ZD1839 (‘Iressa’) is …