Leukotrienes and lipoxins: structures, biosynthesis, and biological effects

B Samuelsson, SE Dahlen, JÅ Lindgren, CA Rouzer… - Science, 1987 - science.org
S.-E. Dahln is an associate professor in theDepartment of … Recently LXA, but not 6(S)-LXA,
has been shown to cause … -derived material and the 6(S) isomer of LXA [6(S)-LXA] does not …

Health effects of diesel exhaust emissions

…, N Stenfors, T Sandström, SE Dahlen - European …, 2001 - Eur Respiratory Soc
Epidemiological studies have demonstrated an association between different levels of air
pollution and various health outcomes including mortality, exacerbation of asthma, chronic …

The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo

N Chiang, CN Serhan, SE Dahlén, JM Drazen… - Pharmacological …, 2006 - ASPET
… Each action of LXA 4 has proven to be stereoselective in that changes in potencies are
associated with double bond isomerization and alcohol chirality (R or S) as well as …

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

…, C Brightling, P Chanez, SE Dahlen… - European respiratory …, 2014 - Eur Respiratory Soc
… year; 4) airflow limitation, ie forced expiratory volume in 1 s (FEV 1 ) <80% predicted (in the
… associated with a reduction in superoxide dismutase and s-nitrosothiol depletion [94, 95]. …

Leukotrienes are potent constrictors of human bronchi

SE Dahlén, P Hedqvist, S Hammarström… - Nature, 1980 - nature.com
… Recently, leukotriene C 4 (LTC 4 :5(s)-hydroxy,6(R)-S-glutathionyl-7,9-trans,11,14-cis-eicosatetraenoic
acid) and D 4 (LTD 4 :5(S)-hydroxy,6(R)-S-cysteinylglycyl-7,9-trans,11,14-cis-…

Chronic rhinosinusitis in Europe – an underestimated disease. A GA2LEN study

…, PJ Bousquet, G Brozek, A Bruno, SE Dahlén… - Allergy, 2011 - Wiley Online Library
To cite this article: Hastan D, Fokkens WJ, Bachert C, Newson RB, Bislimovska J, Bockelbrink
A, Bousquet PJ, Brozek G, Bruno A, Dahlén SE, Forsberg B, Gunnbjörnsdóttir M, Kasper L, …

Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response.

SE Dahlén, J Björk, P Hedqvist… - Proceedings of the …, 1981 - National Acad Sciences
Leukotrienes B4, C4, and D4, members of a recently discovered family of substances
biosynthesized from arachidonic acid, were found to have potent microvascular actions in the …

[HTML][HTML] Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility

…, N Acevedo, M Joerink, G Pershagen, SE Dahlén… - PloS one, 2012 - journals.plos.org
Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be
measured by a large number of methods, now even in a genome-wide manner for hundreds …

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

…, P Chanez, B Dahlén, SE Dahlen… - European …, 2015 - Eur Respiratory Soc
… Participants with asthma had either airflow reversibility (increase in forced expiratory volume
in 1 s (FEV 1 ) >12% predicted or 200 mL following inhalation of 400 µg salbutamol), airway …

Asthma in adults and its association with chronic rhinosinusitis: The GA2LEN survey in Europe

…, M Gunnbjornsdottir, J Minov, G Brozek, SE Dahlen… - Allergy, 2012 - Wiley Online Library
To cite this article: Jarvis D, Newson R, Lotvall J, Hastan D, Tomassen P, Keil T, Gjomarkaj
M, Forsberg B, Gunnbjornsdottir M, Minov J, Brozek G, Dahlen SE, Toskala E, Kowalski ML, …