User profiles for S Radford

Sheena Radford

The University of Leeds
Verified email at leeds.ac.uk
Cited by 35034

A new era for understanding amyloid structures and disease

…, EW Hewitt, NA Ranson, SE Radford - … reviews Molecular cell …, 2018 - nature.com
… In the meantime, Bill Astbury’s pioneering X-ray fibre diffraction studies had shown that
amyloid-like fibrils could be created from normally globular, soluble proteins by denaturing them …

[HTML][HTML] Folding versus aggregation: polypeptide conformations on competing pathways

TR Jahn, SE Radford - Archives of biochemistry and biophysics, 2008 - Elsevier
… These pathological conditions include Alzheimer’s and Parkinson’s diseases, type II … the
yeast/fungal prions Sup35, Ure2 and HET-s), which can assemble into protein aggregates with …

The Yin and Yang of protein folding

TR Jahn, SE Radford - The FEBS journal, 2005 - Wiley Online Library
The study of protein aggregation saw a renaissance in the last decade, when it was discovered
that aggregation is the cause of several human diseases, making this field of research …

How does mindfulness-based cognitive therapy work?

…, RS Taylor, S Byford, A Evans, S Radford… - Behaviour research and …, 2010 - Elsevier
… MBCT’s mechanisms of change. This study determines whether MBCT’s treatment effects …
MBCT’s effects were mediated by enhancement of mindfulness and self-compassion across …

Nucleation of protein fibrillation by nanoparticles

…, S Lindman, E Thulin, SE Radford… - Proceedings of the …, 2007 - National Acad Sciences
… −4 s −1 and 2 × 10 −6 s −1 ), whereas the two association rate constants are 20 and 140 M
−1 ·s −… (off-rate constants 8 × 10 −3 s −1 and 5 × 10 −4 s −1 ), in agreement with other plasma …

The molecular interstellar medium in ultraluminous infrared galaxies

PM Solomon, D Downes, SJE Radford… - The Astrophysical …, 1997 - iopscience.iop.org
… show most of the CO, HCN, 1991; Radford 1991b) and molecular mass is concentrated in a
… In the redshift range cz \ 15,000»80,000 km s~1, our sample has 25 galaxies with 60 km —…

Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes

…, PF Knowles, TCB McLeish, M Pitkeathly, SE Radford - Nature, 1997 - nature.com
… with small oscillatory deformation experiments (5% strain), at a shear rate a of 1 s T ". … (path
length l mm) and a response time of 1 s. Each spectrum was the average offour scans. The …

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

…, PE Fraser, PN Hawkins, CM Dobson, SE Radford… - Nature, 1997 - nature.com
… & Radford, SE Far-UV circular dichroism reveals a conformational switch in a peptide fragment
from the beta-sheet of hen lysozyme. Biochennistry 33,7345–7353 (1994). . Minor, DL Jr …

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

SE Radford, CM Dobson, PA Evans - Nature, 1992 - nature.com
… Formation of the native enzyme is virtually complete in 2 s (ignoring the very slow phase
that was not recorded in our experiments) and each parameter is therefore assigned a value of …

[HTML][HTML] Mindfulness-based cognitive therapy for preventing relapse in recurrent depression: a randomized dismantling trial.

…, C Eames, M Jones, S Radford, S Silverton… - Journal of consulting …, 2014 - psycnet.apa.org
Objective: We compared mindfulness-based cognitive therapy (MBCT) with both cognitive
psychological education (CPE) and treatment as usual (TAU) in preventing relapse to major …