Carcinogenicity and modification of the carcinogenic response by BHA, BHT, and other antioxidants
N Ito, S Fukushima, H Tsuda - CRC Critical reviews in Toxicology, 1985 - Taylor & Francis
V. SUMMARY Carcinogenicity tests showed that addition of the antioxidant BHA to the diet
of F344 rats induced high incidences of papilloma and squamous cell carcinoma of the …
of F344 rats induced high incidences of papilloma and squamous cell carcinoma of the …
Tree of motility–A proposed history of motility systems in the tree of life
…, Y Fukumori, S Fukushima, S Haruta… - Genes to …, 2020 - Wiley Online Library
… Archaea have a proteinaceous S-layer which likely lacks some of the mechanical strength
of the bacterial peptidoglycan layer. It is speculated, from gene homology, that an Asgard-like …
of the bacterial peptidoglycan layer. It is speculated, from gene homology, that an Asgard-like …
Cancer prevention by organosulfur compounds from garlic and onion
S Fukushima, N Takada, T Hori… - Journal of Cellular …, 1997 - Wiley Online Library
… in terms of reduced numbers and areas of liver glutathione S-transferase placental (GST-P) …
Moreover, water-soluble OSCs such as S-methylcysteine and cysteine similarly decreased …
Moreover, water-soluble OSCs such as S-methylcysteine and cysteine similarly decreased …
Design of environment‐sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change
The recent development of biomolecular devices that function within the living body has
required the integration of capabilities for sensing in vivo chemical stimuli, generating detectable …
required the integration of capabilities for sensing in vivo chemical stimuli, generating detectable …
Development of the polymer micelle carrier system for doxorubicin
T Nakanishi, S Fukushima, K Okamoto, M Suzuki… - Journal of Controlled …, 2001 - Elsevier
We show the result of pre-clinical study of NK911, a polymeric micelle carrier system for
doxorubicin (DOX). The NK911 micelle carrier consists of polyethyleneglycol and conjugated …
doxorubicin (DOX). The NK911 micelle carrier consists of polyethyleneglycol and conjugated …
Studies on antioxidants: their carcinogenic and modifying effects on chemical carcinogenesis
N Ito, M Hirose, S Fukushima, H Tsuda, T Shirai… - Food and Chemical …, 1986 - Elsevier
Studies were conducted on the carcinogenic activity of butylated hydroxyanisole (BHA) in
rats and hamsters. To obtain information concerning the mechanism of action of BHA on the …
rats and hamsters. To obtain information concerning the mechanism of action of BHA on the …
Carcinogenicity of butylated hydroxyanisole in F344 rats
N Ito, S Fukushima, A Haqlwara… - Journal of the …, 1983 - academic.oup.com
… None of them detected mutagenic activity on Salmonella typhimurium with S-9 from rat
liver (37, 38). Batzinger et al. (39) and Cumming and Walton (41) found that BHA had …
liver (37, 38). Batzinger et al. (39) and Cumming and Walton (41) found that BHA had …
Doxorubicin-loaded poly (ethylene glycol)–poly (β-benzyl-l-aspartate) copolymer micelles: their pharmaceutical characteristics and biological significance
…, T Okano, Y Sakurai, S Fukushima… - Journal of Controlled …, 2000 - Elsevier
Doxorubicin (DOX) was physically loaded into micelles prepared from poly(ethylene glycol)–poly(β-benzyl-l-aspartate)
block copolymer (PEG–PBLA) by an o/w emulsion method with a …
block copolymer (PEG–PBLA) by an o/w emulsion method with a …
Preparation and biological characterization of polymeric micelle drug carriers with intracellular pH-triggered drug release property: tumor permeability, controlled …
Y Bae, N Nishiyama, S Fukushima… - Bioconjugate …, 2005 - ACS Publications
A novel intracellular pH-sensitive polymeric micelle drug carrier that controls the systemic,
local, and subcellular distributions of pharmacologically active drugs has been developed in …
local, and subcellular distributions of pharmacologically active drugs has been developed in …
Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model
Background— Human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs)
are a promising source of cells for regenerating myocardium. However, several issues, …
are a promising source of cells for regenerating myocardium. However, several issues, …