[HTML][HTML] S-carbocysteine-lysine salt monohydrate and cAMP cause non-additive activation of the cystic fibrosis transmembrane regulator channel in human respiratory …

G Meyer, S Doppierio, L Daffonchio, D Cremaschi - FEBS letters, 1997 - Elsevier
S-Carbocysteine-lysine salt monohydrate (S-CMC-Lys) has been shown to open a Cl −
channel in the trachea, thus aiding fluid secretion. The aim of this study was to characterize the …

Effect of frusemide on Cl-channel in rat peritoneal mast cells

G Meyer, S Doppierio, P Vallin… - European Respiratory …, 1996 - Eur Respiratory Soc
Frusemide can be used as an antiasthma drug and appears to inhibit the release (conditioned
by activation of Cl- channels) of mast cell proinflammatory mediators. We studied the …

[CITATION][C] Localization of large-conductance K+ channels of guinea pig gall-bladder epithelium studied using isolated cells or primary cell cultures

G Meyer, S Doppierio - Bioelectrochemistry and Bioenergetics, 1995 - Elsevier
… The action of Ba2+ is in agreement with its slow blocking which produces well … block is
voltage dependent as noted in many cases [7-101. In intact tissue it has been noted that Ba2+ is

The presence of NHE1 and NHE3 Na+-H+ exchangers and an apical cAMP-independent Cl-channel indicate that both absorptive and secretory functions are present …

C Bazzini, G Bottà, G Meyer, MD Baroni… - Experimental …, 2001 - cambridge.org
… of the corresponding mRNA, is difficult to reconcile with the insensitivity to cAMP shown
under our experimental conditions. A possible explanation is that this channel is always in an …

Plasmodium falciparum likely encodes the principal anion channel on infected human erythrocytes

A Alkhalil, JV Cohn, MA Wagner, JS Cabrera… - Blood, 2004 - ashpublications.org
Invasion by the human malaria parasite, Plasmodium falciparum, is associated with marked
yet selective increases in red blood cell (RBC) membrane permeability. We previously …

An Anion Channel in Guinea Pig Gallbladder Epithelial Cells Is Highly Permeable to HCO− 3

G Meyer, ML Garavaglia, C Bazzini, G Bottà - Biochemical and Biophysical …, 2000 - Elsevier
… ; it is not activated at all by ATP alone, is not inhibited by … is a CFTR homologue is strongly
supported by the results of the RT-PCR experiments. In particular, the fragment we obtained is

S-CMC-Lys protective effects on human respiratory cells during oxidative stress

ML Garavaglia, E Bononi, S Dossena… - Cellular Physiology and …, 2008 - karger.com
S-carbocysteine lysine salt monohydrate (S-CMC-Lys) stimulates glutathione (GSH) efflux
from respiratory cells. Since GSH is … of this study was to evaluate the S-CMC-Lys effects on …

Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells

B Boonyapiwat, P Panagopoulos, H Jones… - Drug metabolism and …, 2005 - degruyter.com
… were in fact S-oxides of SCMC and S-methyl-L-cysteine (SMC) /12/ have since been proved
to be correct /13,14/. The enzyme involved in this biotransformation is under both genetic …

S-CMC-Lys-dependent stimulation of electrogenic glutathione secretion by human respiratory epithelium

F Guizzardi, S Rodighiero, A Binelli, S Saino… - Journal of molecular …, 2006 - Springer
S-carbocysteine lysine salt monohydrate (S-CMC-Lys) can cause an activation of epithelial
Cl − conductance, the purpose of this study was to verify whether S-CMC-Lys is able to …

[CITATION][C] ELSEVIER Bioelectrochemistry and Bioenergetics 36 (1995) 181

…, C Cha, S Da Zhong, G Donelli, XD Dong, S Doppierio… - Bioelectrochemistry and …, 1995