Mass spectrometry is the main analytical technique currently used to address the challenges
of glycomics as it offers unrivalled levels of sensitivity and the ability to handle complex …

Mass spectrometry (MS) of glycoproteins is an emerging field in proteomics, poised to meet
the technical demand for elucidation of the structural complexity and functions of the …

Glycoproteins are known to exhibit multiple biological functions. In order to assign distinct
functional properties to defined structural features, detailed information on the respective …

The dendritic cell specific C-type lectin dendritic cell specific ICAM-3 grabbing non-integrin (DC-SIGN)
binds to “self” glycan ligands found on human cells and to “foreign” glycans of …

Gangliosides, which are sialylated glycosphingolipids, are the major class of glycoconjugates
on neurons and carry the majority of the sialic acid within the central nervous system (CNS)…

Among the large set of cell surface glycan structures, the carbohydrate polymer polysialic
acid (polySia) plays an important role in vertebrate brain development and synaptic plasticity. …

Mass spectrometric techniques are the key technology for rapid and reliable glycan analysis.
However, the lack of robust, dependable, and freely available software for the (semi‐) …

The EUROCarbDB project is a design study for a technical framework, which provides
sophisticated, freely accessible, open-source informatics tools and databases to support …

Adult-onset insulin dependent diabetes mellitus (IDDM) is associated with significant
residual insulin secretion. The process leading to the ultimate destruction of B cells may be …

Polysialic acid (polySia), a post-translational modification of the neural cell adhesion molecule
(NCAM), is the key regulator of NCAM-mediated functions and crucial for normal brain …