Despite extensive evidence showing that exposure to specific chemicals can lead to disease,
current research approaches and regulatory policies fail to address the chemical …

Air pollution affects billions of people worldwide, yet ambient pollution measurements are
limited for much of the world. Urban air pollution concentrations vary sharply over short …

Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in
epidemiological studies. Biomarkers of internal dose, early biological change, susceptibility and …

Background: Previous systematic reviews have indicated that pesticide exposure is possibly
associated with Parkinson disease (PD). However, considerable heterogeneity has been …

Benzene is known to have toxic effects on the blood and bone marrow, but its impact at
levels below the US occupational standard of 1 part per million (ppm) remains uncertain. In a …

The incidence of acute myeloid leukaemia (AML) increases with age and mortality exceeds
90% when diagnosed after age 65. Most cases arise without any detectable early symptoms …

Derived from the term exposure, the exposome is an omic-scale characterization of the
nongenetic drivers of health and disease. With the genome, it defines the phenome of an …

Mechanistic evidence linking chromosomal aberration (CA) to early stages of cancer has been
recently supported by the results of epidemiological studies that associated CA frequency …

We aimed to obtain reliable reference charts for sleep duration, estimate the prevalence of
sleep complaints across the lifespan and identify risk indicators of poor sleep. Studies were …

Background Most studies of the association between diesel exhaust exposure and lung cancer
suggest a modest, but consistent, increased risk. However, to our knowledge, no study to …