Azithromycin is a macrolide antibiotic which inhibits bacterial protein synthesis, quorum-sensing
and reduces the formation of biofilm. Accumulating effectively in cells, particularly …

The outcomes of transplantation vary widely by organ. Lung transplantation (LTx) has rather
poor long-term outcome, with a current median post-transplant survival of 6.0 years. 1, 2 …

Epidemiological and clinical reports indicate that SARS-CoV-2 virulence hinges upon the
triggering of an aberrant host immune response, more so than on direct virus-induced cellular …

Azithromycin reduces airway inflammation and improves forced expiratory volume in 1 s (FEV
1 ) in chronic rejection or bronchiolitis obliterans syndrome (BOS) after lung …

Lung transplantation offers a survival benefit in well chosen patients with end-stage lung
diseases. However, CLAD, side effects of immunosuppressive therapy and solid organ cancer …

Since the inception of lung transplantation (LTx), serial pulmonary function testing (PFT) has
been the primary method of quantifying the physiologic performance of the allograft. The …

Bronchiolitis obliterans syndrome (BOS) is the leading cause of death after lung
transplantation. Treatment is challenging, as the precise pathophysiology remains unclear. We …

Airway colonisation with Pseudomonads, especially Pseudomonas aeruginosa, is common
in lung transplant (LTx) recipients. The current authors investigated whether pseudomonal …

Background Venous thromboembolism (VTE) is a frequent complication of COVID-19, so
that the importance of adequate in-hospital thromboprophylaxis in patients hospitalized with …

Bronchiolitis obliterans syndrome (BOS) is the most important cause of late mortality
following lung transplantation, resulting in major morbidity and a huge burden on healthcare …