[HTML][HTML] Biodistribution and toxicity of pegylated single wall carbon nanotubes in pregnant mice

…, M Massimiani, G Palmieri, R Bernardini… - Particle and fibre …, 2013 - Springer
Background Single wall carbon nanotubes (SWCNTs) are considered promising nanoparticles
for industrial and biomedical applications; however their potential toxicity in several …

[HTML][HTML] Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas

…, P Sacchetti, C Focaccetti, R Bernardini… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The survival rate of head and neck squamous cell carcinomas (HNSCC) patients has not
considerably changed over the last two decades. Polyphenols inhibit the growth of cancer cells…

[HTML][HTML] Adipocyte metabolism is improved by TNF receptor-targeting small RNAs identified from dried nuts

…, S Casciardi, M Potestà, R Bernardini… - Communications …, 2019 - nature.com
There is a growing interest in therapeutically targeting the inflammatory response that underlies
age-related chronic diseases including obesity and type 2 diabetes. Through integrative …

[HTML][HTML] Adoptive cell therapy—harnessing antigen-specific T cells to target solid tumours

…, R Dziadziuszko, C Montesano, R Bernardini… - Cancers, 2020 - mdpi.com
In recent years, much research has been focused on the field of adoptive cell therapies (ACT)
that use native or genetically modified T cells as therapeutic tools. Immunotherapy with T …

[HTML][HTML] Frataxin deficiency induces lipid accumulation and affects thermogenesis in brown adipose tissue

…, M Zingariello, S Morini, R Bernardini… - Cell death & …, 2020 - nature.com
Decreased expression of mitochondrial frataxin (FXN) causes Friedreich’s ataxia (FRDA), a
neurodegenerative disease with type 2 diabetes (T2D) as severe comorbidity. Brown …

Characterization of a new decellularized bovine pericardial biological mesh: Structural and mechanical properties

A Bielli, R Bernardini, D Varvaras, P Rossi… - Journal of the …, 2018 - Elsevier
Implants made from naturally-derived biomaterials, also called biological meshes or biomeshes,
typically derive from decellularized extracellular matrix of either animal or human tissue. …

PKR and GCN2 stress kinases promote an ER stress-independent eIF2α phosphorylation responsible for calreticulin exposure in melanoma cells

…, S Smaili, D Cotella, C Santoro, R Bernardini… - …, 2018 - Taylor & Francis
The immunogenic cell death (ICD) process represents a novel therapeutic approach to treat
tumours, in which cytotoxic compounds promote both cancer cell death and the emission of …

[HTML][HTML] Paternal activation of CB2 cannabinoid receptor impairs placental and embryonic growth via an epigenetic mechanism

…, M Zampieri, G Rossi, R Cicconi, R Bernardini… - Scientific Reports, 2019 - nature.com
The cannabinoid receptor type 2 (CB 2 ) is the peripheral receptor for cannabinoids,
involved in the homeostatic control of several physiological functions. Male mitotic germ cells …

Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against …

…, E Bonanno, R Cicconi, M Mattei, R Bernardini… - Pharmacological …, 2020 - Elsevier
The vascular endothelial growth factor receptor-1 (VEGFR-1) is a membrane receptor for
VEGF-A, placenta growth factor (PlGF) and VEGF-B that plays a crucial role in melanoma …

[HTML][HTML] Exogenous miRNAs from Moringa oleifera Lam. recover a dysregulated lipid metabolism

…, A Minchella, SP Bruno, R Bernardini… - Frontiers in Molecular …, 2022 - frontiersin.org
A balanced diet is critical for human health, and edible plants play an important role in
providing essential micronutrients as well as specific microRNAs (miRNAs) that can regulate …