Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

…, C Arneson, G Grove, S Grossman, R Grover - Critical care …, 2004 - journals.lww.com
Robert Greif, Institut fur Anaesthesiologie u Intensivmed, Wien, Austria; Dr. Anton Hole,
Anestesiavdelingen, Regionsykehuset i Trondheim, Trondheim, Norway; Dr. Lech Krawczyk …

Hypoxic ventilatory drive in normal man

…, B Underhill, GF Filley, RF Grover - The Journal of …, 1970 - Am Soc Clin Investig
A technique is described which permits the inscription of the ventilatory response to
isocapnic hypoxia in man as a continuous curve relating alveolar oxygen tension and minute …

Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs.

…, AB Davidson, JT Reeves, RF Grover - Circulation …, 1976 - Am Heart Assoc
The role of a transmembrane calcium influx in hypoxic pulmonary vasoconstriction was
studied in isolated, blood-perfused, rat lungs. We reasoned that, if the influx of extracellular …

Combination therapy with oral treprostinil for pulmonary arterial hypertension. A double-blind placebo-controlled clinical trial

…, S Zhang, A Khan, CQ Deng, R Grover… - American journal of …, 2020 - atsjournals.org
Rationale: Oral treprostinil improves exercise capacity in patients with pulmonary arterial
hypertension (PAH), but the effect on clinical outcomes was unknown. Objectives: To evaluate …

Administration of the nitric oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the …

J Bakker, R Grover, A McLuckie, L Holzapfel… - Critical care …, 2004 - journals.lww.com
Objective To assess the safety and efficacy of the nitric oxide synthase inhibitor 546C88 in
patients with septic shock. The predefined primary efficacy objective was resolution of shock, …

Abnormal circulatory responses to high altitude in subjects with a previous history of high-altitude pulmonary edema

HN Hultgren, RF GROVER, LH HARTLEY - Circulation, 1971 - Am Heart Assoc
In five men with a history of susceptibility to high-altitude pulmonary edema (HAPE),
hemodynamics and pulmonary gas exchange were measured at sea level, and again 24 hours …

The red cell mass-arterial oxygen relationship in normal man: Application to patients with chronic obstructive airway disease

…, G Jamieson, DW Brown, RF Grover - The Journal of clinical …, 1968 - Am Soc Clin Investig
The normal relationship between red cell mass measured, with 51 chromium-labeled red cells,
and arterial oxygen saturation (Sa O 2 ) over the range from 97.3 to 83.4% was examined …

9 Cardiovascular Adaptation to Exercise at High Altitude

RF GROVER, JV WEIL, JT REEVES - Exercise and sport sciences …, 1986 - journals.lww.com
… Articles in Google Scholar by ROBERT F. … Other articles in this journal by ROBERT F.
GROVER, MD, Ph.D. …

Fluid retention and relative hypoventilation in acute mountain sickness

…, D Rennie, SE Hofmeister, RF Grover, EB Grover… - Respiration, 1982 - karger.com
The presence of pulmonary, cerebral, and/or peripheral edema in acute mountain sickness (AMS)
implies a derangement in the body’s handling of water. Previously, we demonstrated …

Acquired attenuation of chemoreceptor function in chronically hypoxic man at high altitude

…, IE Sodal, GF Filley, RF Grover - The Journal of …, 1971 - Am Soc Clin Investig
To determine whether chronic exposure to hypoxia during adulthood produces alterations in
the control of ventilation, measurements of the resting ventilatory response to hypoxia and …