The humble origins of the propellant driven metered dose inhaler, as a response to a child’s
enquiry, initiated an industry which supplies approximately a half billion inhalers globally for …

The Respimat ® Soft Mist™ Inhaler (SMI) (Boehringer Ingelheim International GmbH,
Ingelheim, Germany) was developed in response to the need for a pocket-sized device that can …

This March 2009 Workshop Summary Report was sponsored by Product Quality Research
Institute (PQRI) based on a proposal by the Inhalation and Nasal Technology Focus Group (…

Background Aerosol and droplet production is inherent to dentistry. Potential for COVID-19
spread through aerosols and droplets characterizes dentistry as having a high risk of …

Study objective: To determine if aerosolizedmedications can be targeted to deposit in the
smaller, peripheralairways or the larger, central airways of adult cystic fibrosis (CF)patients by …

The nasal cavity has a large surface area (150 cm^ sup 2^) available for drug targeting (1).
Gamma scintigraphy has been used as a tool to evaluate nasal deposition of radiolabeled …

Purpose To systematically evaluate the effect of formulation- and administration-related
variables on nasal spray deposition using a nasal cast. Methods Deposition pattern was …

Purpose. To correlate the surface energy of active and carrier components in an aerosol
powder to in vitro performance of a passive dry powder inhaler. Methods. Inverse gas …

Purpose To develop a simple and inexpensive method to visualize and quantify droplet
deposition patterns. Methods Deposition pattern was determined by uniformly coating the nose …

Drugs are given intranasally for both local and systemic applications, and the use of the
intranasal route is predicted to rise dramatically in the next 10 years. Nasal drug delivery may be …