Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria

JP Abrahams, AGW Leslie, R Lutter, JE Walker - Nature, 1994 - nature.com
In the crystal structure of bovine mitochondrial F 1 -ATPase determined at 2.8 Å resolution,
the three catalytic β-subunits differ in conformation and in the bound nucleotide. The structure …

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

…, K Golebski, CM Van Drunen, R Lutter… - Nature …, 2016 - nature.com
Group 2 innate lymphoid cells (ILC2s) secrete type 2 cytokines, which protect against parasites
but can also contribute to a variety of inflammatory airway diseases. We report here that …

IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection

…, M Goldman, HM Jansen, R Lutter… - The Journal of …, 2004 - journals.aai.org
Secondary pneumococcal pneumonia is a serious complication during and shortly after
influenza infection. We established a mouse model to study postinfluenza pneumococcal …

Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin‐(1–7) or an angiotensin II receptor antagonist

RM Wösten‐van Asperen, R Lutter… - The Journal of …, 2011 - Wiley Online Library
Acute respiratory distress syndrome (ARDS) is a devastating clinical syndrome. Angiotensin‐converting
enzyme (ACE) and its effector peptide angiotensin (Ang) II have been implicated …

lnterleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease

…, EA van de Graaf, E Hack, R Lutter… - International archives of …, 1996 - karger.com
We have investigated whether IL-8 is present in airway secretions from patients with asthma
and chronic obstructive pulmonary disease (COPD) to obtain information on its possible role …

[HTML][HTML] Bench-to-bedside review: bacterial pneumonia with influenza-pathogenesis and clinical implications

KF van der Sluijs, T van der Poll, R Lutter… - Critical care, 2010 - Springer
Seasonal and pandemic influenza are frequently complicated by bacterial infections, causing
additional hospitalization and mortality. Secondary bacterial respiratory infection can be …

Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease

…, YS Sabogal Piñeros, R Lutter… - The Journal of …, 2016 - Wiley Online Library
Human respiratory syncytial virus ( RSV ) is the most important cause of severe lower respiratory
tract disease ( LRTD ) in young children worldwide. Extensive neutrophil accumulation …

Oxidative stress and macrophages: driving forces behind exacerbations of asthma and chronic obstructive pulmonary disease?

…, FO Martinez, J Hamann, R Lutter… - … of physiology-lung …, 2019 - journals.physiology.org
Oxidative stress is a common feature of obstructive airway diseases like asthma and chronic
obstructive pulmonary disease (COPD). Lung macrophages are key innate immune cells …

[HTML][HTML] Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in …

S Kezic, GM O'Regan, R Lutter, I Jakasa… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural
moisturizing factor (NMF) components and consequent increased SC pH. Because higher pH …

Procalcitonin vs C-reactive protein as predictive markers of response to antibiotic therapy in acute exacerbations of COPD

JMA Daniels, M Schoorl, D Snijders, DL Knol, R Lutter… - Chest, 2010 - Elsevier
Background Rational prescription of antibiotics in acute exacerbations of COPD (AECOPD)
requires predictive markers. We aimed to analyze whether markers of systemic inflammation …