Thermal stability of calf skin collagen type I in salt solutions

R Komsa-Penkova, R Koynova, G Kostov… - … et Biophysica Acta (BBA …, 1996 - Elsevier
The thermal stability of acid-soluble collagen type I from calf skin in salt solutions is studied
by high-sensitivity differential scanning calorimetry. Three concentration ranges have been …

Modification of Lowry's method for collagen concentration measurement

R Komsa-Penkova, R Spirova, B Bechev - Journal of biochemical and …, 1996 - Elsevier
A procedure for the determination of collagen concentration is described. It is simple and
sensitive and is based on a modification of Lowry's method. The modification includes an initial …

Discrete reduction of type I collagen thermal stability upon oxidation

R Komsa-Penkova, R Koynova, G Kostov… - Biophysical …, 2000 - Elsevier
The oxidation of acid-soluble calf skin collagen type I caused by metal-dependent free
radical generating systems, Fe(II)/H 2 O 2 and Cu(II)/H 2 O 2 , was found to bring down in a …

Inherited thrombophilia and IVF failure: the impact of coagulation disorders on implantation process

…, E Konova, R KomsaPenkova - American journal of …, 2012 - Wiley Online Library
In connection with the embryo acceptance process after IVF procedure, endometrial cells
surface receptors, extracellular matrix ( ECM ) molecules, endothelium and blood circulation …

[HTML][HTML] Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk

…, A Sofroniou, TM Tsvyatkovska, RS Komsa-Penkova… - Fertility and sterility, 2013 - Elsevier
Objective To study the influence of M2/ANXA5 for recurrent pregnancy loss (RPL), according
to the timing of miscarriages and assess the male partner risk. Design Genetic association …

[HTML][HTML] Morphometric and nanomechanical features of platelets from women with early pregnancy loss provide new evidence of the impact of inherited thrombophilia

T Andreeva, R Komsa-Penkova, A Langari… - International journal of …, 2021 - mdpi.com
Pregnancy is associated with hypercoagulation states and increased thrombotic risk,
especially in women with thrombophilia. We combine atomic force microscopy (AFM) and flow …

[HTML][HTML] Morphometric and nanomechanical features of erythrocytes characteristic of early pregnancy loss

A Langari, V Strijkova, R Komsa-Penkova… - International journal of …, 2022 - mdpi.com
Early pregnancy loss (EPL) is estimated to be between 15 and 20% of all adverse pregnancies.
Approximately, half of EPL cases have no identifiable cause. Herein, we apply atomic …

Impact of thrombophilic genetic factors on pulmonary embolism: early onset and recurrent incidences

P Ivanov, R Komsa-Penkova, K Kovacheva, Y Ivanov… - Lung, 2008 - Springer
The importance of genetic thrombophilic factors in the development of venous thromboembolism
has been increasingly recognized. Factor V Leiden (FVL), prothrombin gene mutation …

[HTML][HTML] Altered thermal behavior of blood plasma proteome related to inflammatory cytokines in early pregnancy loss

R Komsa-Penkova, A Danailova, S Krumova… - International Journal of …, 2022 - mdpi.com
Early pregnancy loss (EPL) is a relatively common pathology of which almost 50% of cases
remain idiopathic. In the search for novel biomarkers, differential scanning calorimetry (DSC) …

[HTML][HTML] Membrane Lesions and Reduced Life Span of Red Blood Cells in Preeclampsia as Evidenced by Atomic Force Microscopy

I Giosheva, V Strijkova, R Komsa-Penkova… - International Journal of …, 2023 - mdpi.com
Preeclampsia (PE) presents with maternal de novo hypertension and significant proteinuria
and is one of the leading causes of maternal and perinatal morbidity and mortality with …