User profiles for Raed A Dweik

Raed Dweik

Professor and Chairman, Respiratory Institute (Pulmonary, Critical Care, Infectious Dis …
Verified email at ccf.org
Cited by 23478

An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FeNO) for Clinical Applications

RA Dweik, PB Boggs, SC Erzurum, CG Irvin… - American journal of …, 2011 - atsjournals.org
Background: Measurement of fractional nitric oxide (NO) concentration in exhaled breath (Fe
NO ) is a quantitative, noninvasive, simple, and safe method of measuring airway …

Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program

…, KF Chung, SAA Comhair, RA Dweik… - American journal of …, 2010 - atsjournals.org
Rationale: The Severe Asthma Research Program cohort includes subjects with persistent
asthma who have undergone detailed phenotypic characterization. Previous univariate …

Characterization of the severe asthma phenotype by the national heart, lung, and blood institute's severe asthma research program

…, M Castro, KF Chung, MP Clark, RA Dweik… - Journal of Allergy and …, 2007 - Elsevier
BACKGROUND: Severe asthma causes the majority of asthma morbidity. Understanding
mechanisms that contribute to the development of severe disease is important. OBJECTIVE: …

Detection of lung cancer by sensor array analyses of exhaled breath

…, JK Stoller, J Pyle, J Duncan, RA Dweik… - American journal of …, 2005 - atsjournals.org
Rationale: Electronic noses are successfully used in commercial applications, including
detection and analysis of volatile organic compounds in the food industry. Objectives: We …

Exhaled nitric oxide in pulmonary diseases: a comprehensive review

PJ Barnes, RA Dweik, AF Gelb, PG Gibson, SC George… - Chest, 2010 - Elsevier
The upregulation of nitric oxide (NO) by inflammatory cytokines and mediators in central and
peripheral airway sites can be monitored easily in exhaled air. It is now possible to estimate …

Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

…, C Farver, SL Hazen, C Jennings, RA Dweik… - The FASEB …, 2004 - Wiley Online Library
Pulmonary arterial hypertension (PAH), a fatal disease of unknown etiology characterized
by impaired regulation of pulmonary hemodynamics and vascular growth, is associated with …

Evaluation of delivery of enteral nutrition in critically ill patients receiving mechanical ventilation

…, F Frame, AC Hummell, J Hammel, RA Dweik… - American Journal of …, 2008 - AACN
Background Published reports consistently describe incomplete delivery of prescribed enteral
nutrition. Which specific step in the process delays or interferes with the administration of a …

Alterations of cellular bioenergetics in pulmonary artery endothelial cells

…, AC Arroliga, C Jennings, RA Dweik… - Proceedings of the …, 2007 - National Acad Sciences
Idiopathic pulmonary arterial hypertension (IPAH) is pathogenetically related to low levels of
the vasodilator nitric oxide (NO). Because NO regulates cellular respiration and …

Molecular mechanisms of increased nitric oxide (NO) in asthma: evidence for transcriptional and post-translational regulation of NO synthesis

FH Guo, SAA Comhair, S Zheng, RA Dweik… - The Journal of …, 2000 - journals.aai.org
Evidence supporting increased nitric oxide (NO) in asthma is substantial, although the cellular
and molecular mechanisms leading to increased NO are not known. Here, we provide a …

[HTML][HTML] Eosinophils generate brominating oxidants in allergen-induced asthma

…, MJ Thomassen, CF Farver, RA Dweik… - The Journal of …, 2000 - Am Soc Clin Investig
Eosinophils promote tissue injury and contribute to the pathogenesis of allergen-triggered
diseases like asthma, but the chemical basis of damage to eosinophil targets is unknown. We …