Human inborn errors of immunity (IEI) are a group of 485 distinct genetic disorders affecting
children and adults. Signs and symptoms of IEI are heterogeneous, and accurate diagnosis …

Pediatric eosinophilic pneumonias (EPs) are characterized by a significant infiltration of the
alveolar spaces and lung interstitium by eosinophils, with conservation of the lung structure. …

Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) is a critical regulator of cell
death and inflammation, but its relevance for human disease pathogenesis remains elusive. …

Background X-linked agammaglobulinemia is an inherited immunodeficiency recognized
since 1952. In spite of seven decades of experience, there is still a limited understanding of …

Background Inborn errors of immunity (IEIs) are a heterogeneous group of genetic defects
of immunity, which cause high rates of morbidity and mortality mainly among children due to …

Monogenic immune dysregulation diseases (MIDD) are caused by defective immunotolerance.
This study was designed to increase knowledge on the prevalence and spectrum of …

Background Inborn errors of immunity (IEI) predispose patients to various infectious and non-infectious
complications. Thanks to the development and expanding use of flow cytometry …

Purpose X-linked agammagobulinemia (XLA) is a primary immunodeficiency caused by
Bruton’s tyrosine kinase (BTK) gene defect. XLA patients have absent or reduced number of …

To the Editor: Algeria has been severely affected by the COVID-19 pandemic, with 42 228
cases and 1416 deaths (February 25 to August 25, 2020), and one of the highest incidences …

Objectives To evaluate the diagnostic and predictive contribution of autoantibodies screening
in patients with primary immunodeficiencies (PIDs). Methods In the present study, PID …