Introduction: Adenocarcinoma is the most common histologic type of lung cancer. To
address advances in oncology, molecular biology, pathology, radiology, and surgery of lung …

Background Patients with squamous non-small-cell lung cancer that is refractory to multiple
treatments have poor outcomes. We assessed the activity of nivolumab, a fully human IgG4 …

A collaboration of multidisciplinary experts on the functional evaluation of lung cancer
patients has been facilitated by the European Respiratory Society (ERS) and the European …

Purpose Most crizotinib-treated patients with anaplastic lymphoma kinase gene (ALK)–rearranged
non–small-cell lung cancer (ALK-positive NSCLC) eventually experience disease …

In human cancer, early systemic spread of tumor cells is recognized as a leading cause of
death. Adjuvant therapies are administered to patients after complete resectioning of their …

Cryotherapy, brachytherapy and photodynamic therapy (PDT) are three different methods
proposed in the endoluminal treatment of lung cancers. The current article presents an …

After introduction of the new international guidelines on idiopathic pulmonary fibrosis (IPF)
in 2011, we investigated clinical management practices for patients with IPF according to …

Background: The potential of autofluorescence bronchoscopy (AFB) to detect precancerous
lesions in the central airways and its role in lung cancer screening is uncertain. A study was …

Introduction Afatinib is an effective first-line treatment in patients with epidermal growth factor
receptor (EGFR)-mutated non–small-cell lung cancer (NSCLC) and has shown activity in …

Bile acid biosynthesis is regulated by both feed-forward and feedback mechanisms involving
a cascade of nuclear hormone receptors. Feed-forward regulation of the rate limiting …