Upper airway defence mechanisms

WJ Fokkens, RA Scheeren - Paediatric respiratory reviews, 2000 - Elsevier
The nose is the airconditioner of the airways. Because normal breathing is through the nose,
most airborne particles are filtered there; hence the nasal mucosa is the first line of defence …

Adhesion receptors involved in clustering of blood dendritic cells and T lymphocytes

RA Scheeren, G Koopman… - European journal of …, 1991 - Wiley Online Library
… , efforts to induce VCAM-1 expression on blood DC in vitro by a panel of cytokines, including
IL 1, TNF and GM-CSF have so far been unsuccessful (RA Scheeren, unpublished results). …

Antioxidant levels in the nasal mucosa of patients with chronic sinusitis and healthy controls

…, I Dekker, HP Voss, A Bast, RA Scheeren - … –Head & Neck …, 1997 - jamanetwork.com
Background: Imbalances between oxidant formation and antioxidative defense are associated
with the pathogenesis of several chronic inflammatory disorders of the respiratory tract. …

Inhibition of nitric oxide synthase by nasal decongestants

…, GJ Den Hartog, RA Scheeren… - European …, 2000 - Eur Respiratory Soc
The nasal decongestants oxymetazoline and xylometazoline are frequently used in the
topical treatment of rhinitis and sinusitis. As nitric oxide (NO) is thought to play a role in …

Influence of intranasal steroids during the grass pollen season on bronchial responsiveness in children and young adults with asthma and hay fever

…, AM Fredriks, AF Nagelkerke, RA Scheeren… - Thorax, 2000 - thorax.bmj.com
BACKGROUND It has been reported that intranasal corticosteroids can influence bronchial
hyperresponsiveness (BHR) in asthmatic subjects with seasonal rhinitis. The purpose of the …

Anti-oxidant actions of oxymethazoline and xylomethazoline

GJ Westerveld, RA Scheeren, I Dekker… - European Journal of …, 1995 - Elsevier
Anti-oxidant actions of oxymethazoline and xylomethazoline were investigated by measuring
inhibition io microsomal lipid peroxidation and hydroxyl radical scavenging activity. …

[PDF][PDF] Nasolacrimal duct obstruction caused by an oncocytoma

R de Bree, RA Scheeren, A Kummer, RM Tiwari - Rhinology, 2002 - researchgate.net
We report the case of a woman with epiphora and purulent rhinorrhea for which she initially
underwent a dacryocystorhinostomy. The unilateral rhinorrhea was persistent and one year …

Plasmacytoma of the mastoid bone: solitary and systemic

…, R De Bree, J Janssen, RA Scheeren - The Journal of …, 2000 - cambridge.org
Plasma cell tumours of the mastoid are rare malignancies of haematological origin. Two
patients are described with a plasma cell tumour in the mastoid bone. In one patient it …

Defects in cellular immunity in chronic upper airway infections are associated with immunosuppressive retroviral p15E-like proteins

RA Scheeren, RMJ Keehnen… - … –Head & Neck …, 1993 - jamanetwork.com
• Partial defects in cell-mediated immunity have been shown in patients with chronic purulent
rhinosinusitis. These defects, ie, impaired delayed-type hypersensitivity (type IV) skin …

Distribution of retroviral p15E-related proteins in neoplastic and non-neoplastic human tissues, and their role in the regulation of the immune response

RA Scheeren, RAJ Oostendorp… - Clinical & …, 1992 - academic.oup.com
In patients with head and neck carcinomas and in patients with chronic purulent upper airway
infections, low molecular weight retroviral p15E-like factors are found. These factors are …