Eosinophil priming by cytokines: from cellular signal to in vivo modulation.
…, T Van der Bruggen, RC Schweizer… - The European …, 1996 - europepmc.org
Eosinophils play an important role in the effector phase of allergic inflammation. This review
will focus on the conversion of the unprimed eosinophil phenotype in the peripheral blood of …
will focus on the conversion of the unprimed eosinophil phenotype in the peripheral blood of …
RANTES-and interleukin-8-induced responses in normal human eosinophils: effects of priming with interleukin-5
RC Schweizer, BA Welmers, JA Raaijmakers, P Zanen… - 1994 - ashpublications.org
We report that responses of normal human eosinophils toward the chemokines RANTES
and interleukin-8 (IL-8) are modulated and upregulated by priming with IL-5. In a modified …
and interleukin-8 (IL-8) are modulated and upregulated by priming with IL-5. In a modified …
Analysis of signal transduction pathways in human eosinophils activated by chemoattractants and the T-helper 2–derived cytokines interleukin-4 and interleukin-5
PJ Coffer, RC Schweizer, GR Dubois… - Blood, The Journal …, 1998 - ashpublications.org
Activation and recruitment of eosinophils in allergic inflammation is in part mediated by
chemoattractants and T-helper 2 (Th2)-derived cytokines. However, little is known concerning the …
chemoattractants and T-helper 2 (Th2)-derived cytokines. However, little is known concerning the …
Modulation of eosinophil chemotaxis by interleukin-5
RAJ Warringa, RC Schweizer, T Maikoe… - American journal of …, 1992 - atsjournals.org
Materials and Methods Patients All allergic asthmatic individuals participating in this study
met the American Thoracic Society's definition of asthma, including episodic airway …
met the American Thoracic Society's definition of asthma, including episodic airway …
Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4–Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase …
GR Dubois, RC Schweizer, C Versluis… - American journal of …, 1998 - atsjournals.org
Similar to interleukin-3 (IL-3), IL-5, and granulocyte macrophage colony-stimulating factor (GM-CSF),
IL-4 can be secreted by several cell types involved in allergic inflammatory …
IL-4 can be secreted by several cell types involved in allergic inflammatory …
Steroids induce a disequilibrium of secreted interleukin-1 receptor antagonist and interleukin-1β synthesis by human neutrophils
…, EJD Oudijk, RC Schweizer… - European …, 2011 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) is characterised by neutrophilic inflammation
in the airways and these neutrophils contribute to the production of inflammatory mediators…
in the airways and these neutrophils contribute to the production of inflammatory mediators…
Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals
RC Schweizer, BAC van Kessel-Welmers… - Journal of Leucocyte …, 1996 - academic.oup.com
Eosinophils play an important role in the pathogenesis of allergic diseases such as allergic
asthma. Eosinophil migration in vitro can be divided into directed migration, or Chemotaxis, …
asthma. Eosinophil migration in vitro can be divided into directed migration, or Chemotaxis, …
Expression of activated FcγRII discriminates between multiple granulocyte-priming phenotypes in peripheral blood of allergic asthmatic subjects
…, W ten Hove, B Luijk, C van Aalst, RC Schweizer… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: Allergic asthma is associated with chronic airway and systemic immune
responses. Systemic responses include priming of peripheral blood eosinophils, which is …
responses. Systemic responses include priming of peripheral blood eosinophils, which is …
Diagnosing eosinophilic asthma using a multivariate prediction model based on blood granulocyte responsiveness
…, SJH Vijverberg, J Jansen, L Houben, RC Schweizer… - Allergy, 2017 - Wiley Online Library
Background The identification of inflammatory asthma phenotypes, using sputum analysis,
has proven its value in diagnosis and disease monitoring. However due to technical …
has proven its value in diagnosis and disease monitoring. However due to technical …
[HTML][HTML] The positive effect of dupilumab on comorbid asthma in patients with atopic dermatitis
…, NPA Zuithoff, RC Schweizer… - Clinical and …, 2023 - ncbi.nlm.nih.gov
… Schweizer has nothing to disclose. Marijke Kamsteeg has nothing to disclose. Inge Haeck
is an advisor, consultant, speaker or investigator for Sanofi‐Genzyme, LEO pharma, AbbVie …
is an advisor, consultant, speaker or investigator for Sanofi‐Genzyme, LEO pharma, AbbVie …