User profiles for R. J. Kurukulaaratchy

Ramesh Kurukulaaratchy

University of Southampton
Verified email at soton.ac.uk
Cited by 5154

Early life risk factors for current wheeze, asthma, and bronchial hyperresponsiveness at 10 years of age

SH Arshad, RJ Kurukulaaratchy, M Fenn, S Matthews - Chest, 2005 - Elsevier
Study objectives We sought to identify early life factors (ie, first 4 years) associated with
wheeze, asthma, and bronchial hyperresponsiveness (BHR) at age 10 years, comparing their …

Characterization of wheezing phenotypes in the first 10 years of life

RJ Kurukulaaratchy, MH Fenn… - Clinical & …, 2003 - Wiley Online Library
Background Childhood wheezing illnesses are characterized into different phenotypes.
However, severity of the disease associated with these phenotypes has not been extensively …

Predicting persistent disease among children who wheeze during early life

RJ Kurukulaaratchy, S Matthews… - European …, 2003 - Eur Respiratory Soc
This study sought to determine factors influencing the persistence of early life wheezing up
to the age of 10 yrs and to create a score identifying those with the highest risk of persistent …

Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence

…, N Soto-Ramírez, RJ Kurukulaaratchy… - Journal of Allergy and …, 2014 - Elsevier
Background Filaggrin is an epidermal protein that has a role in skin barrier function. Filaggrin
loss-of-function (FLG-LOF) mutations are a significant risk factor for eczema and atopy, but …

[HTML][HTML] Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3–like protein 1

…, K Izuhara, R Djukanović, RJ Kurukulaaratchy… - Journal of Allergy and …, 2016 - Elsevier
Background Disease heterogeneity in patients with severe asthma and its relationship to
inflammatory mechanisms remain poorly understood. Objective We aimed to identify and …

Developmental trajectories of Body Mass Index from infancy to 18 years of age: prenatal determinants and health consequences

AH Ziyab, W Karmaus, RJ Kurukulaaratchy… - J Epidemiol …, 2014 - jech.bmj.com
Background Knowledge on the long-term development of adiposity throughout childhood/adolescence
and its prenatal determinants and health sequelae is lacking. We sought to (1) …

Influence of atopy and asthma on exhaled nitric oxide in an unselected birth cohort study

…, W Karmaus, F Mitchell, J Grundy, RJ Kurukulaaratchy… - Thorax, 2010 - thorax.bmj.com
Background Asthma is considered to be associated with elevated levels of exhaled nitric
oxide (FeNO). The nature of this relationship and how it is influenced by atopy are still not …

Recent insights into the management of inflammation in asthma

…, A Kyyaly, RJ Kurukulaaratchy - Journal of …, 2021 - Taylor & Francis
The present prevailing inflammatory paradigm in asthma is of T2-high inflammation orchestrated
by key inflammatory cells like Type 2 helper lymphocytes, innate lymphoid cells group 2 …

[HTML][HTML] MicroRNAs—a promising tool for asthma diagnosis and severity assessment: a systematic review

…, SH Arshad, RJ Kurukulaaratchy - Journal of Personalized …, 2022 - mdpi.com
Micro RNAs (miRNAs) are short, non-coding RNAs (Ribonucleic acids) with regulatory
functions that could prove useful as biomarkers for asthma diagnosis and asthma severity-risk …

The influence of gender and atopy on the natural history of rhinitis in the first 18 years of life

RJ Kurukulaaratchy, W Karmaus… - Clinical & …, 2011 - Wiley Online Library
The influence of gender and atopy on the natural history of rhinitis in the first 18 years of life
- Kurukulaaratchy - 2011 - Clinical & Experimental Allergy - Wiley Online Library …