Brain natriuretic peptide is a prognostic parameter in chronic lung disease

HH Leuchte, RA Baumgartner, ME Nounou… - American journal of …, 2006 - atsjournals.org
Rationale: The detection of pulmonary hypertension in patients with chronic lung disease
has prognostic implications. The brain natriuretic peptide (BNP) has been suggested as a …

Clinical significance of brain natriuretic peptide in primary pulmonary hypertension

HH Leuchte, M Holzapfel, RA Baumgartner… - Journal of the American …, 2004 - jacc.org
Objectives : The aim of this study was to investigate the potential role of brain natriuretic
peptide (BNP) levels in the assessment of functional status and right heart performance in …

N-terminal pro-brain natriuretic peptide and renal insufficiency as predictors of mortality in pulmonary hypertension

…, JC Tuerpe, B Hartmann, RA Baumgartner… - Chest, 2007 - Elsevier
Background:N-terminal pro-brain natriuretic peptide (NT-proBNP) is a byproduct of the brain
natriuretic peptide (BNP) that was shown to be of prognostic value in pulmonary …

[HTML][HTML] Mitogen-activated protein (MAP) kinase regulates production of tumor necrosis factor-α and release of arachidonic acid in mast cells: indications of …

C Zhang, RA Baumgartner, K Yamada… - Journal of Biological …, 1997 - ASBMB
Aggregation of the high affinity IgE receptor (FcεRI) in a mast cell line resulted in activation
of the p42 and the stress-activated p38 mitogen-activated protein (MAP) kinases. Selective …

Hemodynamic response to sildenafil, nitric oxide, and iloprost in primary pulmonary hypertension

HH Leuchte, M Schwaiblmair, RA Baumgartner… - Chest, 2004 - Elsevier
Study objectives Different vasodilators and different routes of application are used for the
treatment of primary pulmonary hypertension (PPH). Recently, sildenafil, a phosphodiesterase-…

Inhalation of vasoactive intestinal peptide in pulmonary hypertension

…, C Baezner, RA Baumgartner… - European …, 2008 - Eur Respiratory Soc
Pulmonary hypertension (PH) leads to an increased right ventricular workload, cardiac failure
and death. In idiopathic pulmonary arterial hypertension (PAH) the vasodilating vasoactive …

Characterization of brain natriuretic peptide in long-term follow-up of pulmonary arterial hypertension

HH Leuchte, M Holzapfel, RA Baumgartner, C Neurohr… - Chest, 2005 - Elsevier
Study objectives Pulmonary arterial hypertension (PAH) leads to substantial morbidity and
mortality. Noninvasive parameters in the follow-up assessment of PAH could be helpful in …

Arrhythmias in patients with chronic obstructive pulmonary disease (COPD): occurrence frequency and the effect of treatment with the inhaled long-acting beta2 …

JP Hanrahan, DR Grogan, RA Baumgartner, A Wilson… - Medicine, 2008 - journals.lww.com
Beta-adrenergic stimulation may increase heart rate and the potential for cardiac arrhythmias.
The effect of inhaled long-acting beta2-agonists (LABAs) on these outcomes was …

A dose-escalation study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of 2 and 4 weeks of twice-daily ocular trabodenoson in adults with ocular …

…, W McVicar, CC Rich, RA Baumgartner - Journal of Ocular …, 2016 - liebertpub.com
Purpose: To evaluate the safety and ocular hypotensive efficacy of 4 trabodenoson doses
administered twice daily over 14 or 28 days in subjects with ocular hypertension or primary …

Low-dose levalbuterol in children with asthma: safety and efficacy in comparison with placebo and racemic albuterol

…, G Bensch, KT Kim, R Claus, RA Baumgartner… - Journal of allergy and …, 2001 - Elsevier
Background: Racemic albuterol (RAC) is an equal mixture of (R)-albuterol and (S)-albuterol.
Only the (R)-isomer, levalbuterol (LEV), is therapeutically active. Lower doses of LEV, …