[PDF][PDF] Co-inhibition of CD73 and A2AR adenosine signaling improves anti-tumor immune responses
…, DS Barkauskas, E Sult, C Hay, SJ Blake, Q Huang… - Cancer cell, 2016 - cell.com
Preclinical studies targeting the adenosinergic pathway have gained much attention for
their clinical potential in overcoming tumor-induced immunosuppression. Here, we have …
their clinical potential in overcoming tumor-induced immunosuppression. Here, we have …
Targeting CD73 in the tumor microenvironment with MEDI9447
CM Hay, E Sult, Q Huang, K Mulgrew… - …, 2016 - Taylor & Francis
MEDI9447 is a human monoclonal antibody that is specific for the ectoenzyme CD73 and
currently undergoing Phase I clinical trials. Here we show that MEDI9447 is a potent inhibitor …
currently undergoing Phase I clinical trials. Here we show that MEDI9447 is a potent inhibitor …
[PDF][PDF] Challenges of platooning on public motorways
C Bergenhem, Q Huang, A Benmimoun… - 17th world congress …, 2010 - trimis.ec.europa.eu
Road-trains or platoons present a significant opportunity to both improve traffic efficiency and
to improve the efficiency and safety of vehicles within the platoon. However, for platoons to …
to improve the efficiency and safety of vehicles within the platoon. However, for platoons to …
Effect of chitosan and guar gum based composite edible coating on quality of mushroom (Lentinus edodes) during postharvest storage
Q Huang, X Qian, T Jiang, X Zheng - Scientia Horticulturae, 2019 - Elsevier
The effect of chitosan (CH) (1%) along with guar gum (GG) (5, 15, and 25%) on the quality
of shiitake mushroom (Lentinus edodes) stored at 4 ± 1 C for 16 days was investigated. The …
of shiitake mushroom (Lentinus edodes) stored at 4 ± 1 C for 16 days was investigated. The …
[HTML][HTML] Emerging applications of metabolomics in food science and future trends
W Wu, L Zhang, X Zheng, Q Huang, MA Farag, R Zhu… - Food Chemistry: X, 2022 - Elsevier
Metabolomics is a relatively new component in systems biology that focuses on the high-throughput
characterization of small molecular metabolites in biological systems. It is widely …
characterization of small molecular metabolites in biological systems. It is widely …
[HTML][HTML] MicroRNA-141 promotes the proliferation of non-small cell lung cancer cells by regulating expression of PHLPP1 and PHLPP2
Z Mei, Y He, J Feng, J Shi, Y Du, L Qian, Q Huang… - FEBS letters, 2014 - Elsevier
The dysregulation of microRNAs (miRNAs) is crucially implicated in the development of
various cancers. In this study, we explored the biological role of miR-141 in non-small cell lung …
various cancers. In this study, we explored the biological role of miR-141 in non-small cell lung …
[HTML][HTML] Components of a calmodulin-dependent protein kinase cascade: molecular cloning, functional characterization and cellular localization of Ca2+/calmodulin …
KA Anderson, RL Means, QH Huang, BE Kemp… - Journal of Biological …, 1998 - ASBMB
Ca 2+ /calmodulin-dependent protein kinases I and IV (CaMKI and CaMKIV, respectively)
require phosphorylation on an equivalent single Thr in the activation loop of subdomain VIII for …
require phosphorylation on an equivalent single Thr in the activation loop of subdomain VIII for …
[HTML][HTML] Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling
…, N Holoweckyj, C Hay, M Flynn, Q Huang… - Molecular cancer, 2015 - Springer
Background Monolayer cultures of immortalised cell lines are a popular screening tool for
novel anti-cancer therapeutics, but these methods can be a poor surrogate for disease states, …
novel anti-cancer therapeutics, but these methods can be a poor surrogate for disease states, …
Effect of eugenol fumigation treatment on chilling injury and CBF gene expression in eggplant fruit during cold storage
Q Huang, X Qian, T Jiang, X Zheng - Food chemistry, 2019 - Elsevier
The effect of eugenol (EUG) on chilling injury (CI) to eggplant fruit (Solanum melongena L.)
was investigated. Eggplant fruit were pre-treated with 25 μL/L EUG, and then stored at 4 C for …
was investigated. Eggplant fruit were pre-treated with 25 μL/L EUG, and then stored at 4 C for …
Inhibition of browning and shelf life extension of button mushroom (Agaricus bisporus) by ergothioneine treatment
X Qian, Q Hou, J Liu, Q Huang, Z Jin, Q Zhou… - Scientia …, 2021 - Elsevier
The effect of ergothioneine (EGT) on postharvest quality and possible browning mechanisms
in button mushroom (Agaricus bisporus) was investigated. Mushrooms were sprayed with …
in button mushroom (Agaricus bisporus) was investigated. Mushrooms were sprayed with …