Background Whether the route of early feeding affects outcomes of patients with severe
critical illnesses is controversial. We hypothesised that outcomes were better with early first-line …

Background Acute respiratory distress syndrome (ARDS) is a major complication of COVID-19
and is associated with high mortality and morbidity. We aimed to assess whether …

Introduction Although home non-invasive ventilation (NIV) is increasingly used to manage
patients with chronic ventilatory failure, there are limited data on the long-term outcome of …

Introduction Corticosteroids affect variably survival in sepsis trials, suggesting heterogeneity
in patients’ response to corticosteroids. The RECORDS (Rapid rEcognition of …

Background Patients with obesity are at higher risk for community-acquired and nosocomial
infections. However, no study has specifically evaluated the relationship between obesity …

Dear Editor, Endotracheal intubation (ETI) in ICU is a high-risk procedure [1]. Pre-oxygenation
techniques are needed to prevent life-threatening desaturation. Non-invasive ventilation (…

Improvements in living conditions and increasing life expectancy have combined to result in
ever older patients being admitted to hospital. In parallel, the increasing incidence of cancer, …

Background Microaspiration of gastric and oropharyngeal secretions is the main mechanism
of entry of bacteria into the lower respiratory tract in intubated critically ill patients. The aim …

Introduction Prognosis of patients with COVID-19 depends on the severity of the pulmonary
affection. The most severe cases may progress to acute respiratory distress syndrome (ARDS…

Background Given the pathophysiology of hypoxemia in patients with Covid-19 acute respiratory
failure (ARF), it seemed necessary to evaluate whether ROX index (ratio SpO 2 /FiO 2 …