Heme oxygenase-1 (HO-1) is an intracellular enzyme that degrades heme and inhibits immune
responses and inflammation in vivo. In most cell types, HO-1 is inducible by inflammatory …

The mannose receptor (MR) is a C-type lectin expressed by dendritic cells (DCs). We have
investigated the ability of MR to recognize glycosylated allergens. Using a gene silencing …

Airway remodelling is a critical feature of chronic bronchial diseases, characterised by aberrant
repair of the epithelium and accumulation of fibroblasts, which contribute to extracellular …

Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after
lung transplantation. Chronic lung allograft dysfunction manifests as bronchiolitis obliterans …

Dendritic cells are professional antigen-presenting cells that are specialized in antigen uptake
and presentation. Allergy to cat has increased substantially in recent years and has been …

Background Homeostatic turnover of the extracellular matrix conditions the structure and
function of the healthy lung. In lung transplantation, long-term management remains limited by …

Introduction Oncolytic immunotherapy is based on the use of nonpathogenic replicative
oncolytic viruses that infect and kill tumor cells exclusively. Recently, we found that the …

Attenuated measles virus (MV) is currently being evaluated as an oncolytic virus in clinical
trials and could represent a new therapeutic approach for malignant pleural mesothelioma (…

Dendritic cells (DCs) have been shown to play a key role in the initiation and maintenance
of immune responses to microbial pathogens as well as to allergens, but the exact …

Heterologous polyclonal antibodies might represent an alternative to the use of convalescent
plasma or monoclonal antibodies (mAbs) in coronavirus disease (COVID‐19) by targeting …