… Chez les patients en chirurgie réglée, une baisse de la concentration de fibrinogène est
observée précocement tandis que la thrombocytopénie est plus tardive. Chez les traumatisés …

Hereditary fibrinogen abnormalities comprise two classes of plasma fibrinogen defects:
Type I, afibrinogenemia or hypofibrinogenemia, which has absent or low plasma fibrinogen …

Fibrinogen contributes to thrombosis risk in different ways. Indeed, various mutations in the
fibrinogen genes predispose to thrombosis. At the same time, high levels of fibrinogen are …

Background We designed a simple and integrated diagnostic algorithm for acute venous
thromboembolism based on clinical probability assessment of deep-vein thrombosis (DVT) or …

Little is known about the structure and function of membrane domains in the vacuolar apparatus
of animal cells. A unique feature of late endosomes, which are part of the pathway that …

Objective To develop new antiphospholipid syndrome (APS) classification criteria with high
specificity for use in observational studies and trials, jointly supported by the American …

Objective To assess the safety of a new platelet count threshold for the definition of maternal
thrombocytopenia late in pregnancy. Methods A platelet count was performed in 6770 …

The plasma level of D-dimer, a fibrin degradation product (FDP), is nearly always increased
in the presence of acute pulmonary embolism (PE). Hence, a normal D-dimer level (below a …

Background: Helical computed tomography (CT) is commonly used to diagnose pulmonary
embolism, although its operating characteristics have been insufficiently evaluated. Objective…

Background: Assessment of the clinical probability of pulmonary embolism, plasma D-dimer
measurement, and lower-limb venous compression ultrasonography have all been …