Although it was thought that apoptotic cells, when rapidly phagocytosed, underwent a silent
death that did not trigger an immune response, in recent years a new concept of …

Cell death is an essential phenomenon in normal development and homeostasis, but also
plays a crucial role in various pathologies. Our understanding of the molecular mechanisms …

Raman spectra of biological materials are very complex, because they consist of signals from
all molecules present in cells. In order to obtain chemical information from these spectra, it …

Missense mutations in the CIAS1 gene cause three autoinflammatory disorders: familial
cold autoinflammatory syndrome, Muckle–Wells syndrome and neonatal-onset multiple-system …

Although mixed lineage kinase domain-like (MLKL) protein has emerged as a specific and
crucial protein for necroptosis induction, how MLKL transduces the death signal remains …

Protein kinases of the receptor interacting protein (RIP) family collaborate with death receptor
proteins to regulate cell death. Recent studies (Cho et al., 2009; He et al., 2009; Zhang et al…

Different types of cell death are often defined by morphological criteria, without a clear
reference to precise biochemical mechanisms. The Nomenclature Committee on Cell Death (…

In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations
for the definition of distinct cell death morphologies and for the appropriate use of cell …

For a long time, apoptosis was considered the sole form of programmed cell death during
development, homeostasis and disease, whereas necrosis was regarded as an unregulated …

Cells exposed to extreme physicochemical or mechanical stimuli die in an uncontrollable
manner, as a result of their immediate structural breakdown. Such an unavoidable variant of …