The majority of asthma exacerbations are associated with respiratory virus infections, mostly
rhinoviruses (RVs)[ 1], due to enhanced inflammation in the airways [2]. These occur …

Eleven-nineteen leukemia (ENL) is an epigenetic reader protein that drives oncogenic
transcriptional programs in acute myeloid leukemia (AML). AML is one of the deadliest …

… Dr Peter Adura … I thank my supervisors Profs Ratko Djukanovic and Peter H Howarth for their
support… cell surface antigen presentation leading to cytotoxic T cell lysis of virus infected cells…

RATIONALE: Rhinoviruses are a major cause of asthma exacerbations. Experimental
Rhinovirus (RV) infection has been used as a model to study mechanisms of RV-16-induced …

Cyclic GMP-AMP synthase (cGAS) is the primary sensor for aberrant intracellular dsDNA
producing the cyclic dinucleotide cGAMP, a second messenger initiating cytokine production in …

During host infection, Mycobacterium tuberculosis (Mtb) encounters several types of stress
that impair protein integrity, including reactive oxygen and nitrogen species and …

Soluble adenylyl cyclase (sAC) has gained attention as a potential therapeutic target given
the role of this enzyme in intracellular signaling. We describe successful efforts to design …

In the dynamic landscape of the digital economy, the integration and utilization of Big Data
have emerged as pivotal factors influencing economic growth and innovation. This paper …

… , Tehoe taata no Ierusalema, i haere tia dura i Ieriho, e ati adura i te nana eia, pau i'hora tona
ahu … na tana ea ra, e ia hio adura iana, faaehahau ? adura na tetahi pae ea adura te haere. …

Soluble adenylyl cyclase (sAC: ADCY10) is an enzyme involved in intracellular signaling.
Inhibition of sAC has potential therapeutic utility in a number of areas. For example, sAC is …