User profiles for Peter Openshaw

Peter Openshaw

Professor of Experimental Medicine
Verified email at imperial.ac.uk
Cited by 40972

[PDF][PDF] SARS-CoV-2 Omicron-B. 1.1. 529 leads to widespread escape from neutralizing antibody responses

…, SA Madhi, MC Nunes, T Malik, PJM Openshaw… - Cell, 2022 - cell.com
On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B.1.1.529
was announced, containing far more mutations in Spike (S) than previously reported …

Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study

…, A Ho, CD Russell, J Dunning, PJM Openshaw… - bmj, 2020 - bmj.com
Objective To characterise the clinical features of patients admitted to hospital with coronavirus
disease 2019 (covid-19) in the United Kingdom during the growth phase of the first wave …

[HTML][HTML] Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19

, … Shona C. 12 Openshaw Peter JM 19 Semple … - Nature …, 2020 - nature.com
The development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines
and therapeutics will depend on understanding viral immunity. We studied T cell memory …

Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C …

…, C Sudlow, OV Swann, LCW Turtle, PJM Openshaw… - bmj, 2020 - bmj.com
Objective To develop and validate a pragmatic risk score to predict mortality in patients admitted
to hospital with coronavirus disease 2019 (covid-19). Design Prospective observational …

[HTML][HTML] Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults

…, MG Semple, RC Read, NM Ferguson, PJ Openshaw… - Nature Medicine, 2022 - nature.com
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has caused hundreds of millions of cases and continues to circulate globally. To establish …

[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

…, GP McCann, S Neubauer, PJM Openshaw… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study

…, L Merson, G Carson, J Dunning, PJM Openshaw… - bmj, 2020 - bmj.com
Objective To characterise the clinical features of children and young people admitted to
hospital with laboratory confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-…

Respiratory syncytial virus

…, H Jarvis, C Fraser, P Openshaw - SARS, MERS and other …, 2016 - library.oapen.org
Openshaw PJ, Tregoning JS. Immune responses and disease enhancement during respiratory
syncytial virus … Openshaw PJM. Antiviral immune responses and lung inflammation after …

Tracheostomy in the COVID-19 era: global and multidisciplinary guidance

…, A Donati, M Singer, PJM Openshaw… - The Lancet …, 2020 - thelancet.com
Global health care is experiencing an unprecedented surge in the number of critically ill
patients who require mechanical ventilation due to the COVID-19 pandemic. The requirement …

[HTML][HTML] Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP …

…, JS Nguyen-Van-Tam, PJM Openshaw… - The Lancet …, 2021 - thelancet.com
Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …