User profiles for Patricia Ramos-Ramirez

Patricia Ramos Ramírez

Postdoc, Karolinska Institutet
Verified email at ciencias.unam.mx
Cited by 426

MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation

K Johansson, C Malmhäll, P Ramos-Ramírez… - Journal of Allergy and …, 2017 - Elsevier
Background Allergic airway inflammation is triggered by allergen exposure through several
steps including release of IL-33, which promotes cytokine (IL-5, IL-13) production by type 2 …

[HTML][HTML] Glucocorticoid receptor β (GRβ): beyond its dominant-negative function

P Ramos-Ramírez, O Tliba - International Journal of Molecular Sciences, 2021 - mdpi.com
Glucocorticoids (GCs) act via the GC receptor (GR), a receptor ubiquitously expressed in
the body where it drives a broad spectrum of responses within distinct cell types and tissues, …

[HTML][HTML] Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cells

R Wu, J Högberg, M Adner, P Ramos-Ramírez… - Particle and fibre …, 2020 - Springer
Background Respirable crystalline silica causes lung carcinomas and many thousand
future cancer cases are expected in eg Europe. Critical questions are how silica causes …

[HTML][HTML] Adiponectin/AdipoR1 axis promotes IL-10 release by human regulatory T cells

P Ramos-Ramírez, C Malmhäll, O Tliba… - Frontiers in …, 2021 - frontiersin.org
Background Adiponectin is an important immunomodulatory mediator in inflammatory
conditions. While we previously showed that adiponectin receptor 1 (AdipoR1) is expressed in …

Back to the future: re-establishing guinea pig in vivo asthma models

…, H Meurs, W Ford, P Ramos Ramírez… - Clinical …, 2020 - portlandpress.com
Research using animal models of asthma is currently dominated by mouse models. This has
been driven by the comprehensive knowledge on inflammatory and immune reactions in …

[HTML][HTML] Glucocorticoid insensitivity in asthma: the unique role for airway smooth muscle cells

P Ramos-Ramírez, O Tliba - International journal of molecular sciences, 2022 - mdpi.com
Although most patients with asthma symptoms are well controlled by inhaled glucocorticoids
(GCs), a subgroup of patients suffering from severe asthma respond poorly to GC therapy. …

Bone marrow type 2 innate lymphoid cells: a local source of interleukin‐5 in interleukin‐33‐driven eosinophilia

K Johansson, C Malmhäll, P RamosRamírez… - …, 2018 - Wiley Online Library
T helper type 2 (Th2) cells, type 2 innate lymphoid cells (ILC2s) and eosinophil progenitors
have previously been described to produce interleukin‐5 (IL‐5) in the airways upon allergen …

[HTML][HTML] Lung regulatory T cells express adiponectin receptor 1: modulation by obesity and airway allergic inflammation

P Ramos-Ramírez, C Malmhäll, K Johansson… - International Journal of …, 2020 - mdpi.com
Regulatory T cells (Tregs) decrease in the adipose tissue upon weight gain, contributing to
persistent low-grade inflammation in obesity. We previously showed that adipose tissue …

Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem

Y Amrani, RA Panettieri, P Ramos-Ramirez… - Pharmacology & …, 2020 - Elsevier
Glucocorticoids (GCs) are the treatment of choice for chronic inflammatory diseases such as
asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long-…

A new house dust mite–driven and mast cell–activated model of asthma in the guinea pig

P RamosRamírez, M Noreby, J Liu, J Ji… - Clinical & …, 2020 - Wiley Online Library
Background Animal models are extensively used to study underlying mechanisms in asthma.
Guinea pigs share anatomical, pharmacological and physiological features with human …