User profiles for Patricia Ramos-Ramirez
Patricia Ramos RamírezPostdoc, Karolinska Institutet Verified email at ciencias.unam.mx Cited by 426 |
MicroRNA-155 is a critical regulator of type 2 innate lymphoid cells and IL-33 signaling in experimental models of allergic airway inflammation
Background Allergic airway inflammation is triggered by allergen exposure through several
steps including release of IL-33, which promotes cytokine (IL-5, IL-13) production by type 2 …
steps including release of IL-33, which promotes cytokine (IL-5, IL-13) production by type 2 …
[HTML][HTML] Glucocorticoid receptor β (GRβ): beyond its dominant-negative function
P Ramos-Ramírez, O Tliba - International Journal of Molecular Sciences, 2021 - mdpi.com
Glucocorticoids (GCs) act via the GC receptor (GR), a receptor ubiquitously expressed in
the body where it drives a broad spectrum of responses within distinct cell types and tissues, …
the body where it drives a broad spectrum of responses within distinct cell types and tissues, …
[HTML][HTML] Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cells
R Wu, J Högberg, M Adner, P Ramos-Ramírez… - Particle and fibre …, 2020 - Springer
Background Respirable crystalline silica causes lung carcinomas and many thousand
future cancer cases are expected in eg Europe. Critical questions are how silica causes …
future cancer cases are expected in eg Europe. Critical questions are how silica causes …
[HTML][HTML] Adiponectin/AdipoR1 axis promotes IL-10 release by human regulatory T cells
Background Adiponectin is an important immunomodulatory mediator in inflammatory
conditions. While we previously showed that adiponectin receptor 1 (AdipoR1) is expressed in …
conditions. While we previously showed that adiponectin receptor 1 (AdipoR1) is expressed in …
Back to the future: re-establishing guinea pig in vivo asthma models
Research using animal models of asthma is currently dominated by mouse models. This has
been driven by the comprehensive knowledge on inflammatory and immune reactions in …
been driven by the comprehensive knowledge on inflammatory and immune reactions in …
[HTML][HTML] Glucocorticoid insensitivity in asthma: the unique role for airway smooth muscle cells
P Ramos-Ramírez, O Tliba - International journal of molecular sciences, 2022 - mdpi.com
Although most patients with asthma symptoms are well controlled by inhaled glucocorticoids
(GCs), a subgroup of patients suffering from severe asthma respond poorly to GC therapy. …
(GCs), a subgroup of patients suffering from severe asthma respond poorly to GC therapy. …
Bone marrow type 2 innate lymphoid cells: a local source of interleukin‐5 in interleukin‐33‐driven eosinophilia
T helper type 2 (Th2) cells, type 2 innate lymphoid cells (ILC2s) and eosinophil progenitors
have previously been described to produce interleukin‐5 (IL‐5) in the airways upon allergen …
have previously been described to produce interleukin‐5 (IL‐5) in the airways upon allergen …
[HTML][HTML] Lung regulatory T cells express adiponectin receptor 1: modulation by obesity and airway allergic inflammation
Regulatory T cells (Tregs) decrease in the adipose tissue upon weight gain, contributing to
persistent low-grade inflammation in obesity. We previously showed that adipose tissue …
persistent low-grade inflammation in obesity. We previously showed that adipose tissue …
Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem
Glucocorticoids (GCs) are the treatment of choice for chronic inflammatory diseases such as
asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long-…
asthma. Despite proven effective anti-inflammatory and immunosuppressive effects, long-…
A new house dust mite–driven and mast cell–activated model of asthma in the guinea pig
P Ramos‐Ramírez, M Noreby, J Liu, J Ji… - Clinical & …, 2020 - Wiley Online Library
Background Animal models are extensively used to study underlying mechanisms in asthma.
Guinea pigs share anatomical, pharmacological and physiological features with human …
Guinea pigs share anatomical, pharmacological and physiological features with human …