… and persistence with osteoporosis therapies in order to achieve a significant therapeutic
benefit and thereby reduce the burden that osteoporosis and associated fractures place on …

Background Paget’s disease is a disorder in which there is a marked increase in bone turnover
in localized parts of the skeleton. This results in an abnormal bone leading to expansion, …

Osteomalacia is a generalized bone disorder characterized by impairment of mineralization,
leading to accumulation of unmineralized matrix or osteoid in the skeleton. The classical …

… The reduction in temperature in the placebo group is most likely due to the fact that all patients
… Selby PL 1999) Pamidronate in the treatment of Paget's disease. Bone 24 [Suppl 5]: 575±…

OBJECTIVE To determine factors that might be associated with the development of Charcot
neuroarthropathy. RESEARCH DESIGN AND METHODS This cross-sectional prevalence …

BACKGROUND Patients with cystic fibrosis have several risk factors for the development of
low bone mineral density (BMD). To identify the prevalence and clinical correlates of low …

Bisphosphonates are widely regarded as the treatment of choice for Paget's disease of
bone (PDB) because of their potent inhibitory effects on bone turnover, but the effects of …

The glucose clamp technique is currently regarded as the standard test for measuring
insulin sensitivity against which other methods are compared but is unsuitable for routine …

Evidence suggests that the newly described estrogen receptor β (ER‐β) may be important for
estrogen (17β‐estradiol) action on the skeleton, but its cellular localization in adult human …

To investigate the pathogenesis of osteoporosis in male hypogonadism we have investigated
a heterogeneous group of 13 men with hypogonadism: 7 men (median age 60, range 31–…