An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease

…, T Troosters, I Vogiatzis, PD Wagner - American journal of …, 2014 - atsjournals.org
Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance, …

Measurement of continuous distributions of ventilation-perfusion ratios: theory

PD Wagner, HA Saltzman… - Journal of applied …, 1974 - journals.physiology.org
METHODS Experimental outline. The experimental procedure which provides the data for
the analysis is suitable both for human subjects and experimental animals in health and …

α-fetoprotein, des-γ carboxyprothrombin, and lectin-bound α-fetoprotein in early hepatocellular carcinoma

…, D Normolle, J Dalhgren, D Chia, AS Lok, PD Wagner… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: α-Fetoprotein (AFP) is widely used as a surveillance test for
hepatocellular carcinoma (HCC) among patients with cirrhosis. Des-γ carboxy-prothrombin (DCP) …

Exercise-induced arterial hypoxemia

JA Dempsey, PD Wagner - Journal of applied physiology, 1999 - journals.physiology.org
… Original research of the authors reported in the review was supported by National Heart,
Lung, and Blood Institute Grant HL-17731 for PD Wagner and HL-15469 for JA Dempsey. …

Myoglobin O2 desaturation during exercise. Evidence of limited O2 transport.

…, KF Kendrick, JS Leigh, PD Wagner - The Journal of …, 1995 - Am Soc Clin Investig
The assumption that cellular oxygen pressure (PO2) is close to zero in maximally exercising
muscle is essential for the hypothesis that O2 transport between blood and mitochondria …

Muscle O2 uptake kinetics in humans: implications for metabolic control

…, DR Knight, BK Erickson, PD Wagner - Journal of Applied …, 1996 - journals.physiology.org
Muscle O2 uptake (VO2) kinetics in response to an augmented energetic requirement (on-transition)
has never been directly determined in humans. We have developed a constant-…

Ventilation-perfusion inequality in chronic obstructive pulmonary disease.

PD Wagner, DR Dantzker, R Dueck… - The Journal of …, 1977 - Am Soc Clin Investig
A multiple inert gas elimination method was used to study the mechanism of impaired gas
exchange in 23 patients with advanced chronic obstructive pulmonary disease (COPD). Three …

Continuous Distributions of Ventilation-Perfusion Ratios in Normal Subjects Breathing Air and 100% O2

PD Wagner, RB LARAvuSO, RR Uhi… - The Journal of clinical …, 1974 - Am Soc Clin Investig
A new method has been developed for measuring virtually continuous distributions of
ventilation-perfusion ratios (V̇ A /Q̇) based on the steadystate elimination of six gases of …

Pulmonary gas exchange in humans exercising at sea level and simulated altitude

PD Wagner, GE Gale, RE Moon… - Journal of Applied …, 1986 - journals.physiology.org
In a previous study of normal subjects exercising at sea level and simulated altitude,
ventilation-perfusion (VA/Q) inequality and alveolar-end-capillary O2 diffusion limitation (DIFF) were …

Determinants of maximal oxygen transport and utilization

PD Wagner - Annual review of physiology, 1996 - annualreviews.org
… Wisconsin Press Gonzalez NC, Clancy RL, Wagner PD. 1993. Determinants of maximal …
Hogan MC, Bebout DE, Wagner PD. 1991. Effect of hemoglobin concentration on maximal …