Control of ventilation distribution by selective contraction of different muscle groups was
studied in upright and horizontal postures. Distribution of gas inspired at FRC was more to …

Characteristic patterns of variation over time, namely rhythms, represent a defining feature
of complex systems, one that is synonymous with life. Despite the intrinsic dynamic, …

In asthma, the involvement of airways from the glottis to the alveolar ducts is likely, and the
site of this involvement determines the resulting pathophysiology. The small airways of less …

We have wedged a small catheter in airways 2 to 3 mm in diameter in excised human lungs
to have measure airway resistance central (R c ) and peripheral (R p ) to this site. In five …

… On the other hand, Macklem and Wilson (20) have demonstrated … Macklem and Wilson
(rro), by measuring … Macklem and Mead (unpublished observations) …

To examine the relation between small-airways abnormalities and specific lung functions,
we performed pulmonary-function tests in 36 patients, of whom two were nonsmokers, one to …

MACKLEM, PETER T., AND JERE MEAD. Resistance of central and peripheral airways
measured by a retrograde catheter. J. Appl. Physiol. 22 (3): 3g5-401. rg67.-Pressure in airways …

The time required (tlim) to produce fatigue of the diaphragm was determined in three normal
seated subjects, breathing through a variety of high alinear, inspiratory resistances. During …

Twelve patients exhibiting difficulties during discontinuation of artificial ventilation permitted
us to investigate physical examination techniques used in diagnosing inspiratory muscle …

Cala, SJ, CM Kenyon, G. Ferrigno, P. Carnevali, A. Aliverti, A. Pedotti, PT Macklem, and DF
Rochester. Chest wall and lung volume estimation by optical reflectance motion analysis.J. …