User profiles for P. T. Bozza

Patricia T Bozza

Instituto Oswaldo Cruz, FIOCRUZ
Verified email at ioc.fiocruz.br
Cited by 23956

Lipid droplets in inflammation and cancer

PT Bozza, JPB Viola - … , Leukotrienes and Essential Fatty Acids (PLEFA), 2010 - Elsevier
Accumulation of lipid droplets (also known as lipid bodies or adiposomes) within leukocytes,
epithelial cells, hepatocytes and other non-adipocytic cells is a frequently observed …

[HTML][HTML] Lipid droplets: platforms with multiple functions in cancer hallmarks

…, EA Barreto, NPB Fazolini, JPB Viola, PT Bozza - Cell death & …, 2020 - nature.com
Lipid droplets (also known as lipid bodies) are lipid-rich, cytoplasmic organelles that play
important roles in cell signaling, lipid metabolism, membrane trafficking, and the production of …

Leukocyte lipid bodies—biogenesis and functions in inflammation

PT Bozza, KG Magalhães, PF Weller - … (BBA)-Molecular and Cell Biology of …, 2009 - Elsevier
Lipid body accumulation within leukocytes is a common feature in both clinical and
experimental infectious, neoplasic and other inflammatory conditions. Here, we will review the …

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

…, P Kurtz, FA Bozza, PT Bozza - Blood, The Journal …, 2020 - ashpublications.org
… Rondina, and Alda Bozza for insightful discussions and comments on the work and the
manuscript; the multiuser facility on multiplex analysis and the confocal imaging facility from the …

[HTML][HTML] Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis

…, MT Bozza, HC Castro-Faria-Neto, PT Bozza - Critical care, 2007 - Springer
Introduction The current shortage of accurate and readily available, validated biomarkers of
disease severity in sepsis is an important limitation when attempting to stratify patients into …

[HTML][HTML] Dengue virus capsid protein usurps lipid droplets for viral particle formation

…, G Barbosa-Lima, AT Da Poian, PT Bozza… - PLoS …, 2009 - journals.plos.org
Dengue virus is responsible for the highest rates of disease and mortality among the members
of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating …

[HTML][HTML] Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity

…, EL Azeredo, RMR Nogueira, EF Assis, PT Bozza… - BMC infectious …, 2008 - Springer
Background Dengue virus pathogenesis is not yet fully understood and the identification of
patients at high risk for developing severe disease forms is still a great challenge in dengue …

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

…, DO Nascimento, MBP Soares, PT Bozza… - Nature, 2000 - nature.com
After apoptosis, phagocytes prevent inflammation and tissue damage by the uptake and
removal of dead cells 1 . In addition, apoptotic cells evoke an anti-inflammatory response …

Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense

…, J Vázquez, MA Del Pozo, MJ Sweet, PT Bozza… - Science, 2020 - science.org
INTRODUCTION In all eukaryotic cells, lipid droplets (LDs) store and supply essential lipids
to produce signaling molecules, membrane building blocks, and metabolic energy. The LD …

[HTML][HTML] SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

…, M Miranda, DC Bou-Habib, FA Bozza, PT Bozza… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients. A …