Objectives: To determine the effect of long term inhaled corticosteroids on lung function,
exacerbations, and health status in patients with moderate to severe chronic obstructive …

This study examined health status decline in patients with chronic obstructive pulmonary
disease (COPD). Data are from the Inhaled Steroids in Obstructive Lung Disease (ISOLDE) trial…

Background: A limited or absent bronchodilator response is used to classify chronic obstructive
pulmonary disease (COPD) and can determine the treatment offered. The reliability of the …

The sick building syndrome (SBS) consists of a group of mucosal, skin, and general symptoms
that are temporally related to working in particular buildings. It is the workers who are …

Background: Clinical studies suggest that inhaled corticosteroids reduce exacerbations and
improve health status in chronic obstructive pulmonary disease (COPD). However, their …

This consensus statement provides practical recommendations for specific inhalation
challenge (SIC) in the diagnosis of occupational asthma. They are derived from a systematic …

A young female vaper presented with insidious onset cough, progressive dyspnoea on
exertion, fever, night sweats and was in respiratory failure when admitted to hospital. Clinical …

BACKGROUND--Glutaraldehyde is the best disinfectant for fibreoptic endoscopes. It is also
used in the processing of x ray films. A number of studies have reported eye, nose, and …

Background:There is controversy about whether therapy with inhaled corticosteroids (ICSs)
modifies the natural history of COPD, characterized by an accelerated decline in FEV 1 . …

BACKGROUND: Exposure to chromium during electroplating is a recognised though poorly
characterised cause of occupational asthma. The first series of such patients referred to a …