Shigellosis is a clinical syndrome caused by invasion of the epithelium lining the terminal
ileum, colon, and rectum by Shigella species. Although infections occur globally, and in people …

The production of guidelines for the management of drug-resistant tuberculosis (TB) fits the
mandate of the World Health Organization (WHO) to support countries in the reinforcement of …

Background Shigella infections are a leading cause of diarrhoeal death among children in
low-income and middle-income countries. WHO guidelines reserve antibiotics for treating …

Background Shigella and enterotoxigenic Escherichia coli (ETEC) are bacterial pathogens
that are frequently associated with diarrhoeal disease, and are a significant cause of mortality …

Differences in definitions of acute pediatric diarrhea result in variable estimates of morbidity
and mortality, treatment coverage, and associations with risk factors and outcomes. We …

… Predictors with univariate p-values <0.20 were included in the full model and removed
stepwise using a p-value ≤0.05 until a final parsimonious model was achieved. …

Background: Tuberculosis (TB) causes substantial morbidity and mortality in HIV-infected
children. Sample collection and the paucibacillary nature of TB in children makes diagnosis …

… O'Brien-Fleming boundaries with a two-sided Z score critical value of 2·797 or −2·797 (p
value <0·005) were used to compare the interim analysis p value from a Kaplan-Meier log-rank …

Background Host vulnerabilities associated with acute malnutrition could facilitate the ability
of specific enteric pathogens to cause diarrhoea and associated mortality. Using data from …

Background Shigella is a leading cause of acute watery diarrhea, dysentery, and diarrhea-attributed
linear growth faltering, a precursor to stunting and lifelong morbidity. Several …