Collagenase‐2 (MMP‐8) and collagenase‐3 (MMP‐13) in adult periodontitis: Molecular forms and levels in gingival crevicular fluid and immunolocalisation in gingival …

…, HW Chen, J Wahlgren, P Maisi… - Journal of clinical …, 2002 - Wiley Online Library
… The percentages of MMP‐8 PMN‐type enzyme and MMP‐13 proenzyme bands
correlated significantly with gingival and bleeding indices (p<0.05). Immunohistochemistry …

The in vivo expression of the collagenolytic matrix metalloproteinases (MMP-2,-8,-13, and-14) and matrilysin (MMP-7) in adult and localized juvenile periodontitis

…, P Maisi, T Salo, G Tuter, P Kallio… - Journal of dental …, 2000 - journals.sagepub.com
Periodontal inflammation is characterized by irreversible degradation of periodontal ligament
collagen fibers leading to loss of tooth attachment. Cultured gingival keratinocytes and …

MMP inhibition and downregulation by bisphosphonates

…, R Hanemaaijer, A Teronen, P Maisi… - Annals of the New …, 1999 - Wiley Online Library
Bisphosphonates are a group of drugs capable of inhibiting bone resorption, and are thus
used for the treatment of bone diseases, such as Paget's disease, osteoporosis, and for bone …

Matrix metalloproteinases and tissue inhibitor of metalloproteinase-1 in sarcoidosis and IPF

…, AJ Mackarel, K Prikk, T Sorsa, P Maisi… - European …, 2002 - Eur Respiratory Soc
The purpose of this study was to examine the role of interstitial collagenases, members of the
family of matrix metalloproteinases, in the development of pulmonary fibrosis. The activity, …

Levels and molecular forms of MMP‐7 (matrilysin‐1) and MMP‐8 (collagenase‐2) in diseased human peri‐implant sulcular fluid

M Kivelä‐Rajamäki, P Maisi, R Srinivas… - Journal of …, 2003 - Wiley Online Library
Objectives: Matrix metalloproteinases (MMPs) play crucial role in various tissue destructive
inflammatory processes by degrading almost all peri‐cellular and basement membrane …

Matrix metalloproteinase 2 (gelatinase A) is related to migration of keratinocytes

M Mäkelä, H Larjava, E Pirilä, P Maisi, T Salo… - Experimental cell …, 1999 - Elsevier
… of 20 μM reduced the cell number by about 50% (P … At 20 μM, COL-1 reduced the cell numbers
by about 20% (P … Eccles, SA, Box, GM, Court, WJ, Bone, EA, Thomas, W., and Brown, P. (…

Expression and induction of collagenases (MMP‐8 and‐13) in plasma cells associated with bone‐destructive lesions

J Wahlgren, P Maisi, T Sorsa, M Sutinen… - The Journal of …, 2001 - Wiley Online Library
Matrix metalloproteinases (MMPs) collectively degrade extracellular matrix and basement
membrane proteins in chronic inflammation and bone‐destructive lesions. This study …

[HTML][HTML] Airway obstruction correlates with collagenase-2 (MMP-8) expression and activation in bronchial asthma

K Prikk, P Maisi, E Pirilä, MA Reintam, T Salo… - Laboratory …, 2002 - Elsevier
… that of BALF from controlled BA (p < 0.001). The same … (p < 0.01, p < 0.001, respectively)
and the MMP-8 complex form in uncontrolled BA differed from that of BALF from controlled BA (p

In vivo collagenase‐2 (MMP‐8) expression by human bronchial epithelial cells and monocytes/macrophages in bronchiectasis

K Prikk, E Pirilä, R Sepper, P Maisi… - The Journal of …, 2001 - Wiley Online Library
… A p value of less than 0.05 was considered statistically significant. … elevated in BE BALF
compared with healthy control BALF (p=0.003). The immunoreactivity of the latent and activated …

Laminin‐5 γ2‐chain and collagenase‐2 (MMP‐8) in human peri‐implant sulcular fluid

…, OP Teronen, P Maisi… - Clinical oral implants …, 2003 - Wiley Online Library
Laminin‐5 (LN‐5) is an important epithelial cell‐derived structural and adhesive component
in hemidesmosomes and basement membranes (BM). In peri‐implant tissue, gingival BM …