Occupational asthma

CE Mapp, P Boschetto, P Maestrelli… - American journal of …, 2005 - atsjournals.org
… After Maestrelli and coworkers (368) reported sputum eosinophilia in both early and late
reactors … Maestrelli P. Natural history of adult-onset asthma: insights from model of occupational …

[HTML][HTML] Cellular and structural bases of chronic obstructive pulmonary disease

M Saetta, G Turato, P Maestrelli, CE Mapp… - American journal of …, 2001 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is defined as a disease state characterized
by poorly reversible airflow limitation that is usually both progressive and associated with an …

Mechanisms of occupational asthma

P Maestrelli, P Boschetto, LM Fabbri… - Journal of Allergy and …, 2009 - Elsevier
… In human beings, Del Prete et al 116 and Maestrelli et al 117 observed that the majority
of T-cell clones derived from patients with TDI-induced asthma were CD8 + and capable of …

Airway eosinophilia in chronic bronchitis during exacerbations.

M Saetta, A Di Stefano, P Maestrelli… - American journal of …, 1994 - atsjournals.org
… than did those examined under baseline conditions (p < 0.001). Although to a lesser extent,
the numbers of neutrophils (p < 0.01), T-lymphocytes (CD3) (p < 0.05), VLA-1-positive cells (…

Severity of airflow limitation is associated with severity of airway inflammation in smokers

…, P Balbo, C Vecchio, P Maestrelli… - American journal of …, 1998 - atsjournals.org
… number of neutrophils (p < 0.02), macrophages (p < 0.03), and NK lymphocytes (p < 0.03) in
the subepithelium, and an increased number of MIP-1 α+ epithelial cells (p < 0.02). When all …

Airways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils.

…, S Kostianev, PG Calcagni, LM Fabbri, P Maestrelli - Thorax, 1996 - thorax.bmj.com
… Induction of sputum was performed as described by Maestrelli et al. 5 Briefly, hypertonic
saline was nebulised with an ultrasonic nebuliser (De Vilbiss, Ultra Neb 2000, De Vilbiss Health …

[HTML][HTML] Rescue use of beclomethasone and albuterol in a single inhaler for mild asthma

…, GW Canonica, P Maestrelli, P Paggiaro… - … England Journal of …, 2007 - Mass Medical Soc
Background Treatment guidelines recommend the regular use of inhaled corticosteroids for
patients with mild persistent asthma. We investigated whether the symptom-driven use of a …

Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation

…, F BRACCIONI, CE MAPP, P Maestrelli… - American journal of …, 2000 - atsjournals.org
… The number of CD45 + cells was increased in both smokers with COPD and smokers
with normal lung function as compared with nonsmokers (p < 0.01 and p < 0.05, respectively), …

CD8+ ve cells in the lungs of smokers with chronic obstructive pulmonary disease

…, G Tropeano, CE Mapp, P Maestrelli… - American journal of …, 1999 - atsjournals.org
… CD8 + ve cells were also increased in pulmonary arteries of smokers with COPD as
compared with smokers with normal lung function (p < 0.01). Other inflammatory cells were no …

CD8+ T-Lymphocytes in Peripheral Airways of Smokers with Chronic Obstructive Pulmonary Disease

…, L Corbino, CE Mapp, P Maestrelli… - American journal of …, 1998 - atsjournals.org
To investigate whether the inflammatory process in peripheral airways is different in
smokers who develop symptoms of chronic bronchitis and chronic airflow limitation and in …