[HTML][HTML] Analysis of factors lowering sensitivity of interferon-γ release assay for tuberculosis

…, N Kobayashi, T Shimbo, S Sakurada, PH Thuong… - PloS one, 2011 - journals.plos.org
Background Imperfect sensitivity of interferon-γ release assay (IGRA) is a potential problem
to detect tuberculosis. We made a thorough investigation of the factors that can lead to false …

[HTML][HTML] Mycobacterium tuberculosis strains spreading in Hanoi, Vietnam: Beijing sublineages, genotypes, drug susceptibility patterns, and host factors

S Maeda, NTL Hang, LT Lien, PH Thuong, NV Hung… - Tuberculosis, 2014 - Elsevier
Beijing genotype strains are divided into two major sublineages, ancient (atypical) and modern
(typical) types, but their phenotypic variations remain largely unknown. Mycobacterium …

[HTML][HTML] Primary drug-resistant tuberculosis in Hanoi, Viet Nam: present status and risk factors

NTL Hang, S Maeda, LT Lien, PH Thuong, NV Hung… - PloS one, 2013 - journals.plos.org
Introduction Resistance of Mycobacterium tuberculosis (MTB) to anti-tuberculosis (TB) drugs
presents a serious challenge to TB control worldwide. We investigated the status of drug …

[HTML][HTML] Host-pathogen relationship in retreated tuberculosis with major rifampicin resistance–conferring mutations

NTL Hang, M Hijikata, S Maeda, PH Thuong… - Frontiers in …, 2023 - frontiersin.org
Introduction It is assumed that host defense systems eliminating the pathogen and regulating
tissue damage make a strong impact on the outcome of tuberculosis (TB) disease and that …

[HTML][HTML] Prevalence and associated factors of diabetes mellitus among tuberculosis patients in Hanoi, Vietnam

NB Hoa, PD Phuc, NT Hien, VQ Hoa, PH Thuong… - BMC infectious …, 2018 - Springer
Background Diabetes mellitus (DM) is recognized as an important comorbidity for the
development of tuberculosis (TB). With the increase of DM burden globally, concerns have been …

[HTML][HTML] Whole genome sequencing, analyses of drug resistance-conferring mutations, and correlation with transmission of Mycobacterium tuberculosis carrying katG …

NTL Hang, M Hijikata, S Maeda, PH Thuong… - Scientific reports, 2019 - nature.com
Drug-resistant tuberculosis (TB) is a serious global problem, and pathogen factors involved
in the transmission of isoniazid (INH)-resistant TB have not been fully investigated. We …

[HTML][HTML] Association of IFNGR2 gene polymorphisms with pulmonary tuberculosis among the Vietnamese

…, T Horie, S Sakurada, NP Hoang, PH Thuong… - Human genetics, 2012 - Springer
Interferon-γ (IFN-γ) is a key molecule of T helper 1 (Th1)-immune response against tuberculosis
(TB), and rare genetic defects of IFN-γ receptors cause disseminated mycobacterial …

[HTML][HTML] Inter-rater agreement in the assessment of abnormal chest X-ray findings for tuberculosis between two Asian countries

…, LD Hung, PT Chuc, LT Lien, PH Thuong… - BMC infectious …, 2012 - Springer
Background Inter-rater agreement in the interpretation of chest X-ray (CXR) films is crucial
for clinical and epidemiological studies of tuberculosis. We compared the readings of CXR …

Sublineages of Mycobacterium tuberculosis Beijing genotype strains and unfavorable outcomes of anti-tuberculosis treatment

NTL Hang, S Maeda, N Keicho, PH Thuong, H Endo - Tuberculosis, 2015 - Elsevier
The influence of Mycobacterium tuberculosis (MTB) lineages/sublineages on unfavorable
tuberculosis (TB) treatment outcomes is poorly understood. We investigated the effects of …

[HTML][HTML] Phenotypic and genotypic features of the Mycobacterium tuberculosis lineage 1 subgroup in central Vietnam

…, NTK Diem, NTT Yen, L Van Duc, PH Thuong… - Scientific Reports, 2021 - nature.com
… These genomic characteristics were not found in the non-Vietnamese L1 strains in Thailand,
the Philippines and other areas, but were unique to our L1 subgroup. RD900, another …