The immunosuppressive molecule HLA-G and its clinical implications

…, V Rebmann, J LeMaoult, PA Horn… - Critical reviews in …, 2012 - Taylor & Francis
Human leukocyte antigen G (HLA-G) is a non-classical major histocompatibility complex (MHC)
class I molecule that, through interaction with its receptors, exerts important tolerogenic …

[HTML][HTML] HLA-G as a tolerogenic molecule in transplantation and pregnancy

…, F da Silva Nardi, B Wagner, PA Horn - Journal of immunology …, 2014 - hindawi.com
HLA-G is a nonclassical HLA class I molecule. In allogeneic situations such as pregnancy or
allograft transplantation, the expression of HLA-G has been related to a better acceptance …

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

…, S Radtke, J Ruesing, TR Doeppner, M Epple, PA Horn… - Leukemia, 2014 - nature.com
GV, FF and AI designed the research and wrote the manuscript; FDR, MRC, CR and GS
treated the patients, collected the data and commented on the manuscript; FL and AV collected …

The importance of HLA-G expression in embryos, trophoblast cells, and embryonic stem cells

…, M Vercammen, H Van De Velde, PA Horn… - Cellular and molecular …, 2011 - Springer
The nonclassical HLA-G molecule is a trophoblast-specific molecule present in almost
every pregnancy. It differs from classical HLA class I molecules by the low degree of allelic …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

…, AF Hill, F Hochberg, PA Horn… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

…, AK Ludwig, S Hornung, O Rotan, PA Horn… - Colloids and Surfaces B …, 2011 - Elsevier
Exosomes from three different cell types (HEK 293T, ECFC, MSC) were characterised by
scanning electron microscopy (SEM), dynamic light scattering (DLS) and nanoparticle tracking …

Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression

…, S Radtke, K de Miroschedji, PA Horn… - Stem cells …, 2015 - academic.oup.com
Transplantation of mesenchymal stem cells (MSCs) offers an interesting adjuvant approach
next to thrombolysis for treatment of ischemic stroke. However, MSCs are not integrated into …

Early human cytomegalovirus replication after transplantation is associated with a decreased relapse risk: evidence for a putative virus-versus-leukemia effect in acute …

…, HD Ottinger, RS Ross, PA Horn… - Blood, The Journal …, 2011 - ashpublications.org
The impact of early human cytomegalovirus (HCMV) replication on leukemic recurrence
was evaluated in 266 consecutive adult (median age, 47 years; range, 18-73 years) acute …

Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material

…, R Ferrer-Tur, F Murke, T Tertel, PA Horn… - Journal of …, 2019 - Taylor & Francis
Extracellular vesicles (EVs) mediate targeted cellular interactions in normal and pathophysiological
conditions and are increasingly recognised as potential biomarkers, therapeutic …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles ameliorate inflammation-induced preterm brain injury

…, V Duhan, S Radtke, K De Miroschedji, PA Horn… - Brain, behavior, and …, 2017 - Elsevier
Objective Preterm brain injury is a major cause of disability in later life, and may result in
motor, cognitive and behavioural impairment for which no treatment is currently available. The …