[PDF][PDF] Increased serum nitrite and nitrate levels in patients with cirrhosis: relationship to endotoxemia

C Guarner, G Soriano, A Tomas, O Bulbena… - …, 1993 - Wiley Online Library
Nitric oxide derived from vascular endothelium is a potent vasodilator that plays a key role
in the homeostasis of blood pressure. Because cirrhotic patients tend to have low arterial …

[PDF][PDF] Protective effect of preconditioning on the injury associated to hepatic ischemia‐reperfusion in the rat: role of nitric oxide and adenosine

C Peralta, G Hotter, D Closa, E Gelpí, O Bulbena… - …, 1997 - Wiley Online Library
The effects of ischemic preconditioning on rat liver integrity, as well as the implication of
nitric oxide (NO) and adenosine in this process, has been evaluated. Preconditioning before …

Intratracheal transplantation of alveolar type II cells reverses bleomycin-induced lung fibrosis

…, D Closa, A Xaubet, O Bulbena - American journal of …, 2007 - atsjournals.org
Rationale: Transplantation of stem cells has been proposed as a strategy for repair of lung
fibrosis. Nevertheless, many studies have yielded controversial results that currently limit the …

Heparin mobilizes xanthine oxidase and induces lung inflammation in acute pancreatitis

S Granell, M Gironella, O Bulbena, J Panés… - Critical Care …, 2003 - journals.lww.com
… Granell, S.; Gironella, M.; Bulbena, O.; Panés, J.; Mauri, M.; Sabater, L.; Aparisi, L.; Gelpí,
E.; Closa, Daniel … Closa D, Bulbena O, Hotter G, et al: Xanthine oxidase activation in …

Ischemic preconditioning: a defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion1

C Peralta, O Bulbena, C Xaus, N Prats, JC Cutrin… - …, 2002 - journals.lww.com
Background. Preconditioning protects against both liver and lung damage after hepatic
ischemia-reperfusion (I/R). Xanthine and xanthine oxidase (XOD) may contribute to the …

Losartan attenuates bleomycin induced lung fibrosis by increasing prostaglandin E2 synthesis

M Molina-Molina, A Serrano-Mollar, O Bulbena… - Thorax, 2006 - thorax.bmj.com
Background: The angiotensin system has a role in the pathogenesis of pulmonary fibrosis.
This study examines the antifibrotic effect of losartan, an angiotensin II type 1 receptor …

Oxidised lipids present in ascitic fluid interfere with the regulation of the macrophages during acute pancreatitis, promoting an exacerbation of the inflammatory …

PT Gutierrez, E Folch-Puy, O Bulbena, D Closa - Gut, 2008 - gut.bmj.com
Background: Pancreatitis-associated ascitic fluid (PAAF) plays a critical role in the pathogenesis
of acute pancreatitis. Taking into consideration that damaged pancreas exudes high …

Macrophage activation in exacerbated COPD with and without community-acquired pneumonia

…, D Closa, R Piñer, O Bulbena… - European respiratory …, 2010 - Eur Respiratory Soc
In large series of nonresponding community-acquired pneumonia (CAP) patients, chronic
obstructive pulmonary disease (COPD) was observed to be a protective factor for …

Systemic prostacyclin in cirrhotic patients: relationship with portal hypertension and changes after intestinal decontamination

…, G Soriano, J Such, M Teixidó, I Ramis, O Bulbena… - Gastroenterology, 1992 - Elsevier
The total body production of prostacyclin was shown to be increased in cirrhotic patients,
suggesting that its synthesis by blood vessels of the systemic circulation is enhanced. However, …

Biological consequences of oxygen desaturation and respiratory effort in an acute animal model of obstructive sleep apnea (OSA)

…, JM Montserrat, M Torres, D Navajas, O Bulbena… - Sleep medicine, 2009 - Elsevier
BACKGROUND: An animal model mimicking all the factors involved in obstructive sleep
apnea (OSA) is useful for investigating mechanisms because the associated comorbidity …