User profiles for Olfat Shaker

Olfat Shaker

Medical Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University
Verified email at kasralainy.edu.eg
Cited by 8656

[HTML][HTML] Association of rs6983267 at 8q24, HULC rs7763881 polymorphisms and serum lncRNAs CCAT2 and HULC with colorectal cancer in Egyptian patients

OG Shaker, MA Senousy, EM Elbaz - Scientific Reports, 2017 - nature.com
The impact of HULC rs7763881 on colorectal cancer (CRC) susceptibility is not yet known.
Also, the biological function of the cancer-related rs6983267 remains unclear. We …

Role of microRNAs-29b-2,− 155,− 197 and− 205 as diagnostic biomarkers in serum of breast cancer females

O Shaker, M Maher, Y Nassar, G Morcos, Z Gad - Gene, 2015 - Elsevier
Micro-RNAs (miRs) are known to be differentially expressed in the serum of cancer patients
and controls, and can thus be used as biomarkers for cancer screening. We detected the …

Diagnostic and prognostic role of serum miR‐20b, miR‐17‐3p, HOTAIR, and MALAT1 in diabetic retinopathy

OG Shaker, OO Abdelaleem, RH Mahmoud… - Iubmb …, 2019 - Wiley Online Library
Noncoding RNAs are emerging biomarkers for many diseases including diabetic
retinopathy (DR). This study aimed to measure the expression levels of serum miR‐20b, miR‐17‐3p, …

[HTML][HTML] Circulating microRNA, miR-122 and miR-221 signature in Egyptian patients with chronic hepatitis C related hepatocellular carcinoma

…, A Ammer, H Shehab, O Shaker… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To explore the potential usefulness of serum miR-122 and miR-221 as non-invasive
diagnostic markers of hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC). …

[HTML][HTML] Serum microRNAs as potential biomarkers for early diagnosis of hepatitis C virus-related hepatocellular carcinoma in Egyptian patients

TK Motawi, OG Shaker, SA El-Maraghy, MA Senousy - PloS one, 2015 - journals.plos.org
Circulating microRNAs are deregulated in liver fibrosis and hepatocellular carcinoma (HCC)
and are candidate biomarkers. This study investigated the potential of serum microRNAs; …

[HTML][HTML] Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease

…, E Bugianesi, U Spengler, O Shaker… - Nature …, 2015 - nature.com
Tissue fibrosis is a core pathologic process that contributes to mortality in ~45% of the
population and is likely to be influenced by the host genetic architecture. Here we demonstrate, …

[HTML][HTML] Association between SIRT1 gene polymorphisms and breast cancer in Egyptians

SM Rizk, NN Shahin, OG Shaker - PLoS One, 2016 - journals.plos.org
Background Breast cancer is reported to cause the highest mortality among female cancer
patients. Previous studies have explored the association of silent mating-type information …

[HTML][HTML] Identification of rheumatoid arthritis biomarkers based on single nucleotide polymorphisms and haplotype blocks: a systematic review and meta-analysis

…, MS Mabrouk, AM Eldeib, OG Shaker - Journal of advanced …, 2016 - Elsevier
Genetics of autoimmune diseases represent a growing domain with surpassing biomarker
results with rapid progress. The exact cause of Rheumatoid Arthritis (RA) is unknown, but it is …

Differential microRNAs expression in serum of patients with lung cancer, pulmonary tuberculosis, and pneumonia

AA Abd-El-Fattah, NAH Sadik, OG Shaker… - Cell biochemistry and …, 2013 - Springer
MicroRNAs (miRNAs) play critical regulatory roles in the physiological and pathological
processes. The high stability of miRNAs in human serum represents attractive novel diagnostic …

The multiple faces of nicotine and its implications in tissue and wound repair

JW Martin, SS Mousa, O Shaker… - Experimental …, 2009 - Wiley Online Library
Nicotine, one of the thousands of chemicals in cigarette smoke has a highly debated effect
on cell proliferation and tissue healing. Recent studies documented its pro‐angiogenesis …