[HTML][HTML] Beyond the clot: perfusion imaging of the pulmonary vasculature after COVID-19
…, G Russell, N Dharmarajah, OM Kon - The Lancet …, 2021 - thelancet.com
A compelling body of evidence points to pulmonary thrombosis and thromboembolism as a
key feature of COVID-19. As the pandemic spread across the globe over the past few months…
key feature of COVID-19. As the pandemic spread across the globe over the past few months…
[HTML][HTML] Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential?
Background Nearly two decades after completion of the genome sequence of Mycobacterium
tuberculosis (MTB), and with the advent of next generation sequencing technologies (NGS)…
tuberculosis (MTB), and with the advent of next generation sequencing technologies (NGS)…
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
Tuberculosis (TB), caused by infection with Mycobacterium tuberculosis, is a major cause of
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …
morbidity and mortality worldwide. Efforts to control it are hampered by difficulties with …
Parasitic infections of the lung: a guide for the respiratory physician
H Kunst, D Mack, OM Kon, AK Banerjee, P Chiodini… - Thorax, 2011 - thorax.bmj.com
Parasitic infections of the lung occur worldwide among both immunocompetent and
immunocompromised patients and may affect the respiratory system in a variety of ways. This review …
immunocompromised patients and may affect the respiratory system in a variety of ways. This review …
[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
…, RG Jenkins, C Jolley, S Kerr, OM Kon… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …
hospitalisation with acute disease is not well understood. The aim of this study was to …
[HTML][HTML] Decreased histone deacetylase activity in chronic obstructive pulmonary disease
…, WM Elliott, B Cosio, G Caramori, OM Kon… - … England Journal of …, 2005 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
airway inflammation that is greater in patients with advanced disease. We asked whether there …
airway inflammation that is greater in patients with advanced disease. We asked whether there …
Role of deficient type III interferon-λ production in asthma exacerbations
…, HL Parker, L Slater, A Lewis-Antes, OM Kon… - Nature medicine, 2006 - nature.com
Rhinoviruses are the major cause of asthma exacerbations, and asthmatics have increased
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …
susceptibility to rhinovirus and risk of invasive bacterial infections. Here we show deficient …
Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
…, PS Jeetley, P Kanagaratnam, OM Kon… - European heart …, 2021 - academic.oup.com
Background Troponin elevation is common in hospitalized COVID-19 patients, but underlying
aetiologies are ill-defined. We used multi-parametric cardiovascular magnetic resonance (…
aetiologies are ill-defined. We used multi-parametric cardiovascular magnetic resonance (…
IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo
…, NW Bartlett, MR Edwards, OM Kon… - American journal of …, 2014 - atsjournals.org
Rationale: Rhinoviruses are the major cause of asthma exacerbations; however, its
underlying mechanisms are poorly understood. We hypothesized that the epithelial cell–derived …
underlying mechanisms are poorly understood. We hypothesized that the epithelial cell–derived …
Outgrowth of the bacterial airway microbiome after rhinovirus exacerbation of chronic obstructive pulmonary disease
…, MB Trujillo-Torralbo, S Elkin, OM Kon… - American journal of …, 2013 - atsjournals.org
Rationale: Rhinovirus infection is followed by significantly increased frequencies of positive,
potentially pathogenic sputum cultures in chronic obstructive pulmonary disease (COPD). …
potentially pathogenic sputum cultures in chronic obstructive pulmonary disease (COPD). …