Mixed phenotype acute leukaemia (MPAL) is a high-risk subtype of leukaemia with myeloid
and lymphoid features, limited genetic characterization, and a lack of consensus regarding …

Early T‐cell precursor acute lymphoblastic leukaemia (ETP‐ALL) is a recently identified
subtype of T‐ALL with distinctive gene expression and cell marker profiles, poor response to …

Fusion genes involving ZNF384 have recently been identified in B-cell precursor acute
lymphoblastic leukemia, and 7 fusion partners have been reported. We further characterized this …

Clear cell sarcoma of the kidney (CCSK) is one of the major pediatric renal neoplasms, but
its associated genetic abnormalities are largely unknown. We identified internal tandem …

The glycosylphosphatidylinositol-anchored CD24 protein is a B cell differentiation Ag that is
expressed on mature resting B cells but disappears upon Ag stimulation. We used Burkitt’s …

Overexpression of c-erbB-2 (also known as HER-2/neu) has been found in many human
cancers, including head and neck squamous cell carcinoma (SCC). We therefore examined …

The outcome of treatment-refractory and/or relapsed pediatric T cell acute lymphoblastic
leukemia (T-ALL) is extremely poor 1 , and the genetic basis for this is not well understood. Here …

Shiga toxin (Stx) binds to the receptor glycolipid Gb3Cer on the cell surface and is responsible
for hemolytic uremic syndrome. Stx has two isoforms, Stx1 and Stx2, and in clinical …

Acute erythroid leukemia (AEL) is a high-risk leukemia of poorly understood genetic basis,
with controversy regarding diagnosis in the spectrum of myelodysplasia and myeloid leukemia…

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the
potential to differentiate into all cell lineages, including hepatocytes, in vitro. Induced …