User profiles for Nikolaos Balatsos
Nikolaos AA BalatsosDepartment of Biochemistry and Biotechnology, University of Thessaly, Larissa, Greece Verified email at bio.uth.gr Cited by 718 |
[HTML][HTML] Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC)
NAA Balatsos, P Nilsson, C Mazza, S Cusack… - Journal of Biological …, 2006 - ASBMB
Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3′-exoribonuclease.
Here we have investigated how the cap binding complex (CBC) affects human …
Here we have investigated how the cap binding complex (CBC) affects human …
Alterations of deadenylase expression in acute leukemias: evidence for poly (a)-specific ribonuclease as a potential biomarker
…, P Matsouka, KI Gourgoulianis, NAA Balatsos - Acta …, 2012 - karger.com
Background/Aims: The degradation of mRNA is a key process in the control of gene expression
correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is …
correlated to anomalous cell proliferation. The rate-limiting step of mRNA degradation is …
[HTML][HTML] Poly (A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: prognostic value and impact on gene expression
Background Lung cancer is the leading cause of cancer mortality worldwide, mainly due to
late diagnosis, poor prognosis and tumor heterogeneity. Thus, the need for biomarkers that …
late diagnosis, poor prognosis and tumor heterogeneity. Thus, the need for biomarkers that …
Competitive inhibition of human poly (A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides
Poly(A)-specific ribonuclease (PARN) is a cap-interacting deadenylase that mediates, together
with other exonucleases, the eukaryotic mRNA turnover and thus is actively involved in …
with other exonucleases, the eukaryotic mRNA turnover and thus is actively involved in …
Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation
Five ribofuranosyl pyrimidine nucleosides and their corresponding 1,2,3-triazole derivatives
have been synthesized and characterized. Their inhibitory action to Ribonuclease A has …
have been synthesized and characterized. Their inhibitory action to Ribonuclease A has …
Cysteinyl leukotriene receptors in tonsillar B-and T-lymphocytes from children with obstructive sleep apnea
…, G Rassidakis, NAA Balatsos… - Sleep medicine, 2012 - Elsevier
OBJECTIVES: Cysteinyl leukotrienes have been implicated in the pathogenesis of
adenotonsillar hypertrophy in children with obstructive sleep apnea (OSA). This study aimed to …
adenotonsillar hypertrophy in children with obstructive sleep apnea (OSA). This study aimed to …
[HTML][HTML] A multifunctional RNA recognition motif in poly (A)-specific ribonuclease with cap and poly (A) binding properties
…, N Henriksson, A Niedzwiecka, NAA Balatsos… - Journal of biological …, 2007 - ASBMB
Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive and cap-interacting 3′
exoribonuclease that efficiently degrades mRNA poly(A) tails. Here we show that the RNA …
exoribonuclease that efficiently degrades mRNA poly(A) tails. Here we show that the RNA …
Expression of leukotriene biosynthetic enzymes in tonsillar tissue of children with obstructive sleep apnea: a prospective nonrandomized study
…, L Lianou, P Maragozidis, NAA Balatsos… - … –Head & Neck …, 2014 - jamanetwork.com
Importance Cysteinyl leukotrienes (CysLTs) potentially promote adenotonsillar hypertrophy
in children with obstructive sleep apnea (OSA). Previous studies have identified CysLTs and …
in children with obstructive sleep apnea (OSA). Previous studies have identified CysLTs and …
Positioning Europe for the EPITRANSCRIPTOMICS challenge
…, Y Motorin, JY Roignant, N Balatsos… - RNA biology, 2018 - Taylor & Francis
The genetic alphabet consists of the four letters: C, A, G, and T in DNA and C,A,G, and U in
RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins …
RNA. Triplets of these four letters jointly encode 20 different amino acids out of which proteins …
A comprehensive phylogenetic analysis of deadenylases
…, D Vlachakis, NAA Balatsos… - Evolutionary …, 2013 - journals.sagepub.com
Deadenylases catalyze the shortening of the poly(A) tail at the messenger ribonucleic acid (mRNA)
3′-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and …
3′-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and …