Long-term outcome and safety of prolonged bedaquiline treatment for multidrug-resistant tuberculosis
…, C Bernard, N Veziris… - European …, 2017 - Eur Respiratory Soc
Bedaquiline, a recently approved drug for the treatment of multidrug-resistant tuberculosis (MDR-TB),
is recommended for a duration of 24 weeks. There are scarce data on patients …
is recommended for a duration of 24 weeks. There are scarce data on patients …
Assessment of Clarithromycin Susceptibility in Strains Belonging to the Mycobacterium abscessus Group by erm(41) and rrl Sequencing
S Bastian, N Veziris, AL Roux, F Brossier… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Clarithromycin was the drug of choice for Mycobacterium abscessus infections until
inducible resistance due to erm(41) was described. Because M. abscessus was split into M. …
inducible resistance due to erm(41) was described. Because M. abscessus was split into M. …
[HTML][HTML] Outcomes of bedaquiline treatment in patients with multidrug-resistant tuberculosis
…, M Fréchet-Jachym, J Robert, N Veziris… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
Bedaquiline is recommended by the World Health Organization for the treatment of
multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). We pooled data …
multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB). We pooled data …
Should moxifloxacin be used for the treatment of extensively drug-resistant tuberculosis? An answer from a murine model
…, V Jarlier, R Farinotti, N Veziris - Antimicrobial agents …, 2010 - Am Soc Microbiol
The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is
resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. …
resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. …
Performance of the New Version (v2.0) of the GenoType MTBDRsl Test for Detection of Resistance to Second-Line Drugs in Multidrug-Resistant Mycobacterium …
…, A Pham, F Reibel, W Sougakoff, N Veziris… - Journal of clinical …, 2016 - Am Soc Microbiol
Detecting resistance to fluoroquinolones (FQ) and second-line injectable drugs (amikacin [AMK],
kanamycin [KAN], and capreomycin [CAP]) is crucial given the worldwide increase in …
kanamycin [KAN], and capreomycin [CAP]) is crucial given the worldwide increase in …
Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
…, L Trieu, ZF Udwadia, TS van der Werf, N Veziris… - The Lancet, 2018 - thelancet.com
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs, …
to estimate the association of treatment success and death with the use of individual drugs, …
The Peptidoglycan of Stationary-Phase Mycobacterium tuberculosis Predominantly Contains Cross-Links Generated by l,d-Transpeptidation
…, M Fourgeaud, L Dubost, A Marie, N Veziris… - Journal of …, 2008 - Am Soc Microbiol
Our understanding of the mechanisms used by Mycobacterium tuberculosis to persist in a “dormant”
state is essential to the development of therapies effective in sterilizing tissues. …
state is essential to the development of therapies effective in sterilizing tissues. …
Novel Gyrase Mutations in Quinolone-Resistant and -Hypersusceptible Clinical Isolates of Mycobacterium tuberculosis: Functional Analysis of Mutant Enzymes
A Aubry, N Veziris, E Cambau… - Antimicrobial Agents …, 2006 - Am Soc Microbiol
Mutations in the DNA gyrase GyrA 2 GyrB 2 complex are associated with resistance to
quinolones in Mycobacterium tuberculosis. As fluoroquinolones are being used increasingly in …
quinolones in Mycobacterium tuberculosis. As fluoroquinolones are being used increasingly in …
Detection by GenoType MTBDR sl Test of complex mechanisms of resistance to second-line drugs and ethambutol in multidrug-resistant Mycobacterium tuberculosis …
F Brossier, N Veziris, A Aubry, V Jarlier… - Journal of clinical …, 2010 - Am Soc Microbiol
The GenoType MTBDRsl test rapidly detects resistance to ethambutol, fluoroquinolones,
and second-line aminoglycosides (amikacin and kanamycin) and cyclic peptide (capreomycin) …
and second-line aminoglycosides (amikacin and kanamycin) and cyclic peptide (capreomycin) …
Compassionate use of bedaquiline for the treatment of multidrug-resistant and extensively drug-resistant tuberculosis: interim analysis of a French cohort
…, B Henry, D Martin, E Caumes, N Veziris… - Clinical Infectious …, 2015 - academic.oup.com
In a cohort of 35 patients with multidrug-resistant and extensively drug-resistant tuberculosis,
individually tailored bedaquiline-containing regimens led to culture conversion in 97% of …
individually tailored bedaquiline-containing regimens led to culture conversion in 97% of …