Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory
diseases and a major cause of morbidity and mortality worldwide. Disturbed innate immune …

Background Chronic obstructive pulmonary disease (COPD) is characterized by excessive
inflammation and disturbed bacterial clearance in the airways. Although cigarette smoke (CS) …

Cigarette smoking is associated with increased inflammation and defective antibacterial
responses in the airways. Interestingly, vitamin D has been shown to suppress inflammation and …

Rationale Antielastin autoimmunity has been hypothesised to drive disease progression in
chronic obstructive pulmonary disease (COPD). The proposed mechanism is currently …

Introduction Non-small cell lung cancer (NSCLC) is a heterogeneous disorder consisting of
distinct molecular subtypes each characterised by specific genetic and epigenetic profiles. …

Physical inactivity is an important contributor to skeletal muscle weakness, osteoporosis,
and weight loss in chronic obstructive pulmonary disease. However, the effects of physical …

Chronic obstructive pulmonary disease (COPD) is associated with skeletal muscle
dysfunction. Vitamin D plays an important role in muscle strength and performance in healthy …

Chronic obstructive pulmonary disease (COPD), which is characterized by an excessive
inflammatory response of the airways, is often complicated by exacerbations. Vitamin D …

We greatly appreciate the call for cautious interpretation of the Anticoagulation Effectiveness
(ACE) results by Dr. Tzouvelekis and colleagues. As we highlighted in the DISCUSSION …

Nicotine, an important component of cigarette smoke, is a neurotransmitter that contributes
to stress, depression and anxiety in smokers. In rodents, it increases anxiety and reduces …