[HTML][HTML] Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations
…, I Romieu, DJ Van Den Berg, D Hu, NN Hansel… - Nature …, 2011 - ncbi.nlm.nih.gov
Asthma is a common disease with a complex risk architecture including both genetic and
environmental factors. We performed a meta-analysis of North American genome-wide …
environmental factors. We performed a meta-analysis of North American genome-wide …
Severe Community-Onset Pneumonia in Healthy Adults Caused by Methicillin-Resistant Staphylococcus aureus Carrying the Panton-Valentine Leukocidin Genes
…, G Sinha, T Ross, M Cai, NN Hansel… - Clinical infectious …, 2005 - academic.oup.com
Background . Recent worldwide reports of community-onset skin abscesses, outbreaks of
furunculosis, and severe pneumonia associated with methicillin-resistant Staphylococcus …
furunculosis, and severe pneumonia associated with methicillin-resistant Staphylococcus …
Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission
…, FME Franssen, U Frey, ML Han, NN Hansel… - The Lancet, 2022 - thelancet.com
Despite substantial progress in reducing the global impact of many non-communicable
diseases, including heart disease and cancer, morbidity and mortality due to chronic respiratory …
diseases, including heart disease and cancer, morbidity and mortality due to chronic respiratory …
[HTML][HTML] Clinical significance of symptoms in smokers with preserved pulmonary function
…, JL Curtis, NA Gouskova, NN Hansel… - … England Journal of …, 2016 - Mass Medical Soc
Background Currently, the diagnosis of chronic obstructive pulmonary disease (COPD)
requires a ratio of forced expiratory volume in 1 second (FEV 1 ) to forced vital capacity (FVC) of …
requires a ratio of forced expiratory volume in 1 second (FEV 1 ) to forced vital capacity (FVC) of …
Detectable clonal mosaicism from birth to old age and its relationship to cancer
We detected clonal mosaicism for large chromosomal anomalies (duplications, deletions
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …
and uniparental disomy) using SNP microarray data from over 50,000 subjects recruited for …
[HTML][HTML] The clinical features of the overlap between COPD and asthma
M Hardin, EK Silverman, RG Barr, NN Hansel… - Respiratory …, 2011 - Springer
Background The coexistence of COPD and asthma is widely recognized but has not been
well described. This study characterizes clinical features, spirometry, and chest CT scans of …
well described. This study characterizes clinical features, spirometry, and chest CT scans of …
[HTML][HTML] Airway mucin concentration as a marker of chronic bronchitis
…, CB Cooper, MLK Han, NN Hansel… - … England Journal of …, 2017 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic
bronchitic and emphysematous components. In one biophysical model, the concentration of …
bronchitic and emphysematous components. In one biophysical model, the concentration of …
[HTML][HTML] Assembly of a pan-genome from deep sequencing of 910 humans of African descent
…, A Mayorga, J Knight-Madden, T Hartert, NN Hansel… - Nature …, 2019 - nature.com
We used a deeply sequenced dataset of 910 individuals, all of African descent, to construct
a set of DNA sequences that is present in these individuals but missing from the reference …
a set of DNA sequences that is present in these individuals but missing from the reference …
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
…, PS Bakke, JD Crapo, TH Beaty, NN Hansel… - Nature …, 2017 - nature.com
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association discovery …
and is the third leading cause of death globally. Through genome-wide association discovery …
Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study
…, L Zhang, J Murphy, NN Hansel… - American journal of …, 2011 - atsjournals.org
Rationale: The characterization of young adults who develop late-onset diseases may
augment the detection of novel genes and promote new pathogenic insights. Methods: We …
augment the detection of novel genes and promote new pathogenic insights. Methods: We …