… Tsuno, Besset, and Ritchie have no significant commercial relationships to disclose
relative to this article. Corresponding author and reprints: Norifumi Tsuno, MD, Inserm E0361, …

… These data indicate that AdipoR1 and AdipoR2 are integral membrane proteins—the N
terminus was internal and the C terminus was external, which is opposite to the topology of all …

Depression and dementia, in particular Alzheimer’s disease (AD), are critically important
issues in the mental health of old age. Both conditions apparently reduce quality of life and …

Background Transfusion‐related acute lung injury (TRALI) is currently one of the most
common causes of transfusion‐related major morbidity and death. Among the many TRALI …

Background Chloroquine (CQ), the worldwide used anti-malarial drug, has recently being
focused as a potential anti-cancer agent as well as a chemosensitizer when used in …

Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs),
known to inhibit cyclooxygenase (COX), reduce the risk of colorectal cancer. COX is a …

IL-17A is a T cell-derived proinflammatory cytokine that contributes to the pathogenesis of
rheumatoid arthritis. Recently, six related molecules have been identified to form the IL-17 …

… These data are compatible with our findings that cell migration was most markedly stimulated
at 10 nm, whereas cell proliferation, cell adhesion, and secretion of both VEGF and IL-8 …

BACKGROUND: Epigallocatechin gallate (EGCG), the major component of tea polyphenol,
has been reported to have various physiologic modulatory activities. Several reports also …

Recently, apoptosis has been implicated as one of the end points of cells exposed to
chemotherapeutic agents. The p53 and Bcl-2 family of proteins are involved in chemotherapy-…