User profiles for N. Lachmann

Nico Lachmann

Priv.-Doz. Hannover Medical School
Verified email at mh-hannover.de
Cited by 2290

Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantation

…, N Lachmann, T Mohanakumar, N Suciu-Foca… - …, 2013 - journals.lww.com
Background The introduction of solid-phase immunoassay (SPI) technology for the detection
and characterization of human leukocyte antigen (HLA) antibodies in transplantation while …

Luminex® and its applications for solid organ transplantation, hematopoietic stem cell transplantation, and transfusion

N Lachmann, K Todorova, H Schulze… - Transfusion Medicine …, 2013 - karger.com
The detection of antibodies against the human leukocyte antigen (HLA) complex has become
indispensable in every clinical practice. The development of solid-phase assays like the …

Continuous human iPSC-macrophage mass production by suspension culture in stirred tank bioreactors

…, H Kempf, R Zweigerdt, N Lachmann - Nature protocols, 2022 - nature.com
Macrophages derived from human induced pluripotent stem cells (iPSCs) have the potential
to enable the development of cell-based therapies for numerous disease conditions. We …

Lost in translation: pluripotent stem cell‐derived hematopoiesis

…, S Liebhaber, JH Klusmann, N Lachmann - EMBO molecular …, 2015 - embopress.org
Pluripotent stem cells ( PSC s) such as embryonic stem cells or induced pluripotent stem cells
represent a promising cell type to gain novel insights into human biology. Understanding …

[HTML][HTML] Impaired humoral and cellular immunity after SARS-CoV-2 BNT162b2 (tozinameran) prime-boost vaccination in kidney transplant recipients

…, S Lukassen, D Stauch, N Lachmann… - The Journal of …, 2021 - Am Soc Clin Investig
… (B) Sera of KTx patients available from day 23 ± 5 after boost immunization were retested
for reactivity as in A with n = 24. (C) Serological reactivity was quantified only in responding …

[PDF][PDF] The stomatal response to reduced relative humidity requires guard cell-autonomous ABA synthesis

…, S Sonnewald, U Sonnewald, S Kneitz, N Lachmann… - Current Biology, 2013 - cell.com
… After experiencing a shift in rh from 85% to 35%, Col 0 and aba3-1 exhibit a loss of K+;
aba3-1 guard cell K+ content was higher under control and stress conditions than WT (n R 6 6 …

Anti-human leukocyte antigen and donor-specific antibodies detected by luminex posttransplant serve as biomarkers for chronic rejection of renal allografts

N Lachmann, PI Terasaki, K Budde, L Liefeldt… - …, 2009 - journals.lww.com
… In this failure group, the incidence of DSA was 21.2% (n=45) compared with 6.0% (n=48) of
… For a smaller number of HLAab negative patients (n=195), we were able to test a second …

[HTML][HTML] Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation

…, P Glander, J Waiser, N Lachmann… - American journal of …, 2012 - Elsevier
Donor-specific HLA antibodies (DSA) have a negative impact on kidney graft survival. Therefore,
we analyzed the occurrence of DSA and antibody-mediated rejection (AMR) in patients …

Pulmonary macrophage transplantation therapy

T Suzuki, P Arumugam, T Sakagami, N Lachmann… - Nature, 2014 - nature.com
Bone-marrow transplantation is an effective cell therapy but requires myeloablation, which
increases infection risk and mortality. Recent lineage-tracing studies documenting that …

Autopsy findings in patients on postcardiotomy extracorporeal membrane oxygenation (ECMO)

…, N Lachmann, T Walther, N Doll… - … journal of artificial …, 2006 - journals.sagepub.com
Objectives To assess the clinical sensitivity of causes of death, concomitant diseases and
postoperative complications including thromboembolic events in ECMO patients. Methods: …